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7OBD

Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide and stabilizer Fusicoccin-A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A14-3-3 protein sigmapolymer25328226.51UniProt (P31947)
Pfam (PF00244)
In PDB
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2BRho-related GTP-binding protein RhoEpolymer111348.51UniProt (P61587)
In PDB
Homo sapiensProtein MemB,Rho family GTPase 3,Rho-related GTP-binding protein Rho8,Rnd3
3AFUSICOCCINnon-polymer680.81Chemie (FSC)
4AMAGNESIUM IONnon-polymer24.32Chemie (MG)
5ACHLORIDE IONnon-polymer35.51Chemie (CL)
6BFARNESYLnon-polymer206.41Chemie (FAR)
7waterwater18.0321Chemie (HOH)
Sequence modifications
A: 1 - 248 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29575.0
Non-Polymers*Number of molecules5
Total formula weight971.3
All*Total formula weight30546.2
*Water molecules are not included.

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PDB entries from 2024-06-12

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