7OB8
Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer Fusicoccin-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | LDB1 phosphopeptide | polymer | 11 | 1257.2 | 1 | UniProt (Q86U70) | Homo sapiens | LIM domain-binding protein 1,LDB-1,Carboxyl-terminal LIM domain-binding protein 2,CLIM-2,LIM domain-binding factor CLIM2,hLdb1,Nuclear LIM interactor |
| 3 | C (A) | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) PubChem (46936214) PubChem (24124005) PubChem (44201245) PubChem (52940549) PubChem (57061783) PubChem (58892803) PubChem (143471529) PubChem (89167108) PubChem (89358776) PubChem (270757) PubChem (71308204) PubChem (447573) PubChem (89352860) PubChem (89424149) PubChem (91305733) PubChem (5381214) PubChem (124914704) PubChem (124914702) PubChem (125183286) PubChem (6437071) PubChem (134693211) PubChem (12309993) PubChem (138107212) PubChem (11534864) PubChem (124914703) PubChem (124914705) PubChem (146157920) PubChem (163008024) PubChem (134688043) PubChem (163008025) PubChem (163728719) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29483.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 764.9 | |
| All* | Total formula weight | 30248.6 |
