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7OB5

Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer25328226.51UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
LDB1 phosphopeptidepolymer111257.21UniProt (Q86U70)Homo sapiensLIM domain-binding protein 1,LDB-1,Carboxyl-terminal LIM domain-binding protein 2,CLIM-2,LIM domain-binding factor CLIM2,hLdb1,Nuclear LIM interactor
3C, D
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
4E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7H, I
(A, P)
waterwater18.0410Chemie (HOH)
Sequence modifications
A: 1 - 248 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29483.7
Non-Polymers*Number of molecules5
Total formula weight232.0
All*Total formula weight29715.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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