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7OA4

Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(AAA, BBB, DDD, GGG)
N-terminal endonuclease domain of La Crosse virus L-proteinpolymer18421722.64UniProt (A5HC98)
Pfam (PF15518)
Bunyavirus La CrosseProtein L,Large structural protein,Replicase,Transcriptase,RNA-directed RNA polymerase L
2E, J, N, S
(AAA, BBB, DDD, GGG)
(2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acidnon-polymer413.94Chemie (0N8)
3F, G, K, O, P...
(AAA, BBB, DDD, GGG)
FORMIC ACIDnon-polymer46.06Chemie (FMT)
4H, I, L, M, Q...
(AAA, BBB, DDD, GGG)
MANGANESE (II) IONnon-polymer54.98Chemie (MN)
5W, X, Y, Z
(AAA, BBB, DDD, GGG)
waterwater18.0102Chemie (HOH)
Sequence modifications
AAA, BBB, DDD, GGG: 1 - 183 (UniProt: A5HC98)
PDBExternal DatabaseDetails
Gly 0-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight86890.4
Non-Polymers*Number of molecules18
Total formula weight2371.2
All*Total formula weight89261.7
*Water molecules are not included.

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