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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7O9K

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1039S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
In PDB		Homo sapiens (Human)MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
2a39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
In PDB		Homo sapiens (Human)MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
3139S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
In PDB		Homo sapiens (Human)MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
4239S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
In PDB		Homo sapiens (Human)MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
5339S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
In PDB		Homo sapiens (Human)MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
6439S ribosomal protein L36, mitochondrialpolymer10311809.31UniProt (Q9P0J6)
Pfam (PF00444)
In PDB		Homo sapiens (Human)MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m
7539S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
In PDB		Homo sapiens (Human)MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
8639S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
In PDB		Homo sapiens (Human)MRP-L38,Mitochondrial large ribosomal subunit protein mL38
9739S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)
In PDB		Homo sapiens (Human)MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
10839S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
In PDB		Homo sapiens (Human)MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
11939S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
In PDB		Homo sapiens (Human)MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
12A16S rRNApolymer1559500033.61Homo sapiens
13A15-methylcytosine rRNA methyltransferase NSUN4polymer38443140.51UniProt (Q96CB9)
Pfam (PF01189)
In PDB		Homo sapiens (Human)NOL1/NOP2/Sun domain family member 4
14BMT-TRNAVALpolymer6922022.11GenBank (1485738021)Homo sapiens
15A2Transcription termination factor 4, mitochondrialpolymer38144012.51UniProt (Q7Z6M4)
Pfam (PF02536)
In PDB		Homo sapiens (Human)Mitochondrial transcription termination factor 4,mTERF domain-containing protein 2
16CMitochondrial ribosome-associated GTPase 1polymer33437292.71UniProt (Q9BT17)
Pfam (PF01926)
In PDB		Homo sapiens (Human)GTP-binding protein 7,Mitochondrial GTPase 1
17D39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Homo sapiens (Human)MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
18E39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
In PDB		Homo sapiens (Human)MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
19F39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
In PDB		Homo sapiens (Human)MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
20FF, t1, t2, t3, t4...39S ribosomal protein L12, mitochondrialpolymer19821378.27UniProt (P52815)
Pfam (PF16320)
Pfam (PF00542)
In PDB		Homo sapiens (Human)MRP-L12,5c5-2,Mitochondrial large ribosomal subunit protein bL12m
21GMitochondrial ribosome-associated GTPase 2polymer41445015.31UniProt (Q9H4K7)
Pfam (PF01018)
Pfam (PF01926)
In PDB		Homo sapiens (Human)GTP-binding protein 5,Protein obg homolog 1,ObgH1
22H39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
In PDB		Homo sapiens (Human)MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
23I39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
In PDB		Homo sapiens (Human)MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
24J39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Homo sapiens (Human)MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
25K39S ribosomal protein L13, mitochondrialpolymer17820723.01UniProt (Q9BYD1)
Pfam (PF00572)
In PDB		Homo sapiens (Human)MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
26L39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
In PDB		Homo sapiens (Human)MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
27M39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
In PDB		Homo sapiens (Human)MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
28N39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
In PDB		Homo sapiens (Human)MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
29O39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
In PDB		Homo sapiens (Human)MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
30PMitochondrial ribosomal protein L18, isoform CRA_bpolymer17920465.31UniProt (A8K9D2)
Pfam (PF00861)
In PDB		Homo sapiens (Human)cDNA FLJ76688,highly similar to Homo sapiens HSPC071 mRNA
31Q39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
In PDB		Homo sapiens (Human)MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
32R39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
In PDB		Homo sapiens (Human)MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
33S39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
In PDB		Homo sapiens (Human)MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
34T39S ribosomal protein L22, mitochondrialpolymer21224369.51UniProt (E7ESL0)
Pfam (PF00237)
In PDB		Homo sapiens (Human)
35U39S ribosomal protein L23, mitochondrialpolymer15317807.21UniProt (Q16540)
Pfam (PF00276)
In PDB		Homo sapiens (Human)MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
36V39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Homo sapiens (Human)MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
37W39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
In PDB		Homo sapiens (Human)MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
38X39S ribosomal protein L28, mitochondrialpolymer25630202.91UniProt (Q13084)
Pfam (PF00830)
In PDB		Homo sapiens (Human)MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
39Y39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
In PDB		Homo sapiens (Human)MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
40Z39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
In PDB		Homo sapiens (Human)MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
41b39S ribosomal protein L43, mitochondrialpolymer21523457.81UniProt (Q8N983)
Pfam (PF05047)
In PDB		Homo sapiens (Human)MRP-L43,Mitochondrial large ribosomal subunit protein mL43,Mitochondrial ribosomal protein bMRP36a
42c39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
In PDB		Homo sapiens (Human)MRP-L44,Mitochondrial large ribosomal subunit protein mL44
43d39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
In PDB		Homo sapiens (Human)MRP-L45,Mitochondrial large ribosomal subunit protein mL45
44e39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
In PDB		Homo sapiens (Human)MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
45f39S ribosomal protein L48, mitochondrialpolymer21223970.81UniProt (Q96GC5)
Pfam (PF00338)
In PDB		Homo sapiens (Human)MRP-L48,Mitochondrial large ribosomal subunit protein mL48
46g39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
In PDB		Homo sapiens (Human)MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
47h39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
In PDB		Homo sapiens (Human)MRP-L50,Mitochondrial large ribosomal subunit protein mL50
48i39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
In PDB		Homo sapiens (Human)MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
49j39S ribosomal protein L52, mitochondrialpolymer12313682.71UniProt (Q86TS9)
Pfam (PF18699)
In PDB		Homo sapiens (Human)L52mt,MRP-L52,Mitochondrial large ribosomal subunit protein mL52
50k39S ribosomal protein L53, mitochondrialpolymer11212125.91UniProt (Q96EL3)
Pfam (PF10780)
In PDB		Homo sapiens (Human)MRP-L53,Mitochondrial large ribosomal subunit protein mL53
51l39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
In PDB		Homo sapiens (Human)MRP-L54,Mitochondrial large ribosomal subunit protein mL54
52m39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
In PDB		Homo sapiens (Human)MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
53nrRNA methyltransferase 2, mitochondrialpolymer24627464.71UniProt (Q9UI43)
Pfam (PF01728)
In PDB		Homo sapiens (Human)16S rRNA (uridine(1369)-2'-O)-methyltransferase,16S rRNA [Um1369] 2'-O-methyltransferase,Protein ftsJ homolog 2
54oRibosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
In PDB		Homo sapiens (Human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
55pPeptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
In PDB		Homo sapiens (Human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
56qGrowth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
In PDB		Homo sapiens (Human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein
57r39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
In PDB		Homo sapiens (Human)S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
58s39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
In PDB		Homo sapiens (Human)S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
59tElongation factor Tu, mitochondrialpolymer45249613.51UniProt (P49411)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF03143)
In PDB		Homo sapiens (Human)EF-Tu,P43
60uMitochondrial assembly of ribosomal large subunit protein 1polymer23426203.11UniProt (Q96EH3)
Pfam (PF02410)
In PDB		Homo sapiens (Human)
61vMIEF1 upstream open reading frame proteinpolymer708460.81UniProt (L0R8F8)
Pfam (PF05347)
In PDB		Homo sapiens (Human)
62wAcyl carrier protein, mitochondrialpolymer15617434.31UniProt (O14561)
Pfam (PF00550)
In PDB		Homo sapiens (Human)ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit
63UNKUNKpolymer282401.01Homo sapiens
640, 4ZINC IONnon-polymer65.42Chemie (ZN)
65A, D, E, G, M...MAGNESIUM IONnon-polymer24.393Chemie (MG)
66A1S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
67C, tGUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
68GGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
69nS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
70w4'-PHOSPHOPANTETHEINEnon-polymer358.31Chemie (PNS)
Sequence modifications
G: 1 - 406 (UniProt: Q9H4K7)
PDBExternal DatabaseDetails
Asp 407-expression tag
Tyr 408-expression tag
Lys 409-expression tag
Asp 410-expression tag
Asp 411-expression tag
Asp 412-expression tag
Asp 413-expression tag
Lys 414-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains69
Total formula weight2191333.9
Non-Polymers*Number of molecules101
Total formula weight4942.0
All*Total formula weight2196275.9
*Water molecules are not included.

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PDB entries from 2024-07-17

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