7O7Z
Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A2 | 18S rRNA | polymer | 1870 | 603928.3 | 1 | GenBank (GBCT01000564.1) | Oryctolagus cuniculus | |
| 2 | AA | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 3 | AB | Ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 4 | AC | Ribosomal protein S27a | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 5 | AD | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 6 | AE | Ribosomal protein eS26 | polymer | 115 | 13047.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 7 | AF | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 8 | AG | uS14 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 9 | AH | mRNA containing SARS-CoV-2 sequence | polymer | 220 | 70601.5 | 1 | GenBank (NC_045512.2) | Severe acute respiratory syndrome coronavirus 2 | |
| 10 | AI | E-site tRNA | polymer | 76 | 15209.5 | 1 | Bos taurus | ||
| 11 | AT | P-site Phe-tRNA(Phe) | polymer | 76 | 24889.1 | 1 | Bos taurus | ||
| 12 | AZ | 40S ribosomal protein SA | polymer | 295 | 32970.0 | 1 | UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB | Oryctolagus cuniculus (Rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
| 13 | Aa | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 14 | Ab | Ribosomal protein uS5 | polymer | 293 | 31285.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 15 | Ac | 40S ribosomal protein S3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 16 | Ad | Ribosomal protein eS4 | polymer | 263 | 29654.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 17 | Ae | Ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 18 | Af | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 19 | Ag | 40S ribosomal protein S7 | polymer | 432 | 47356.2 | 1 | UniProt (G1SVB0) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 20 | Ah | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 1 | UniProt (G1TJW1) Pfam (PF01201) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 21 | Ai | Ribosomal protein S9 (Predicted) | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 22 | Aj | eS10 | polymer | 165 | 18933.8 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 23 | Ak | 40S ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 24 | Al | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 25 | Am | uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 26 | An | 40S ribosomal protein uS11 | polymer | 151 | 16302.8 | 1 | UniProt (G1T1F0) Pfam (PF00411) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 27 | Ao | 40S ribosomal protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 28 | Ap | uS9 | polymer | 172 | 19213.5 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 29 | Aq | 40S ribosomal protein eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 30 | Ar | 40S ribosomal protein S18 | polymer | 152 | 17801.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 31 | As | Ribosomal protein eS19 | polymer | 145 | 16104.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 32 | At | 40S ribosomal protein uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 33 | Au | Ribosomal protein eS21 | polymer | 83 | 9181.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 34 | Av | Ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 35 | Aw | 40S ribosomal protein S23 | polymer | 143 | 15860.7 | 1 | UniProt (G1SZ47) Pfam (PF00164) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 36 | Ax | 40S ribosomal protein S24 | polymer | 130 | 15107.9 | 1 | UniProt (G1T3D8) Pfam (PF01282) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 37 | Ay | 40S ribosomal protein S25 | polymer | 124 | 13645.0 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 38 | Az | 60s ribosomal protein l41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) In PDB | Oryctolagus cuniculus (Rabbit) | eL41 |
| 39 | B5 | 28S rRNA | polymer | 4808 | 1557519.5 | 1 | GenBank (GBCN01009604.1) | Oryctolagus cuniculus | |
| 40 | B7 | 5S | polymer | 120 | 38851.9 | 1 | GenBank (GBCM01014045.1) | Oryctolagus cuniculus | |
| 41 | B8 | 5.8S rRNA | polymer | 158 | 50809.0 | 1 | GenBank (GBCN01009604.1) | Oryctolagus cuniculus | |
| 42 | BA | Ribosomal protein uL2 | polymer | 257 | 28103.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 43 | BB | Ribosomal protein L3 | polymer | 403 | 46121.0 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 44 | BC | 60S ribosomal protein L4 | polymer | 413 | 46430.9 | 1 | UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 45 | BD | Ribosomal_L18_c domain-containing protein | polymer | 297 | 34523.9 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 46 | BE | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 47 | BF | Ribosomal Protein uL30 | polymer | 247 | 29201.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 48 | BG | Ribosomal protein eL8 | polymer | 266 | 30061.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 49 | BH | 60S ribosomal protein L9 | polymer | 192 | 21871.4 | 1 | UniProt (G1SWI6) Pfam (PF00347) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 50 | BI | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L10 (Predicted) |
| 51 | BJ | Ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 52 | BK | Replicase polyprotein 1ab | polymer | 1071 | 121565.8 | 1 | UniProt (P0DTD1) Pfam (PF09401) Pfam (PF06478) Pfam (PF00680) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | pp1ab,ORF1ab polyprotein |
| 53 | BL | Ribosomal protein eL13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 54 | BM | Ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 55 | BN | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 56 | BO | Ribosomal protein uL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 57 | BP | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) UniProt (by SIFTS) (G1SCJ6) Pfam (PF00237) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 58 | BQ | Ribosomal Protein eL18 | polymer | 188 | 21699.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 59 | BR | 60S ribosomal protein L19 | polymer | 196 | 23535.3 | 1 | UniProt (Q3T0W9) Pfam (PF01280) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 60 | BS | Ribosomal protein eL20 | polymer | 176 | 20749.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 61 | BT | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 62 | BU | Ribosomal protein eL22 | polymer | 128 | 14756.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 63 | BV | Ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 64 | BW | eL24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 65 | BX | uL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 66 | BY | Ribosomal protein L26 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 67 | BZ | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 68 | Ba | 60S ribosomal protein L27a | polymer | 148 | 16635.6 | 1 | UniProt (G1SNY0) Pfam (PF00828) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 69 | Bb | 60S ribosomal protein L29 | polymer | 245 | 26721.7 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 70 | Bc | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 71 | Bd | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 72 | Be | eL32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) UniProt (by SIFTS) (G1TUN8) Pfam (PF01655) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 73 | Bf | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 74 | Bg | 60S ribosomal protein L34 | polymer | 117 | 13326.1 | 1 | UniProt (G1TXG5) Pfam (PF01199) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 75 | Bh | uL29 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 76 | Bi | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 77 | Bj | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 78 | Bk | eL38 | polymer | 70 | 8238.9 | 1 | UniProt (G1U001) Pfam (PF01781) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 79 | Bl | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 80 | Bm | 60S ribosomal protein L40 | polymer | 128 | 14800.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 81 | Bo | eL42 | polymer | 106 | 12490.0 | 1 | UniProt (G1U344) UniProt (by SIFTS) (G1T040) Pfam (PF00935) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 82 | Bp | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 83 | Br | Ribosomal protein eL28 | polymer | 137 | 15844.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 84 | Bs | 60S acidic ribosomal protein P0 | polymer | 318 | 34380.5 | 1 | UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 85 | Bt | Ribosomal protein L12 | polymer | 165 | 17847.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 86 | Bv | Ribosomal protein uL1 | polymer | 217 | 24875.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 87 | B5, A2 | SPERMIDINE | non-polymer | 145.2 | 30 | Chemie (SPD) | |||
| 88 | B5, A2 | SPERMINE | non-polymer | 202.3 | 3 | Chemie (SPM) | |||
| 89 | A2, B8, B5, BR, BV... | MAGNESIUM ION | non-polymer | 24.3 | 420 | Chemie (MG) | |||
| 90 | B5, BQ, A2, BT, B8... | UNKNOWN ATOM OR ION | non-polymer | 329 | Chemie (UNX) | ||||
| 91 | AC, AE, AG, Bg, Bj... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 92 | water | water | 18.0 | 2117 | Chemie (HOH) |
Sequence modifications
A2: 1 - 1870 (GenBank: GBCT01000564.1)
AH: 3326 - 3545 (GenBank: NC_045512.2)
Ah: 1 - 208 (UniProt: G1TJW1)
B5: 1 - 4808 (GenBank: GBCN01009604.1)
BD: 1 - 297 (UniProt: G1SYJ6)
Bk: 1 - 70 (UniProt: G1U001)
| PDB | External Database | Details |
|---|---|---|
| B8n 1249 | C 3623 | conflict |
| 4ac 1338 | C 3712 | conflict |
| 4ac 1843 | C 4217 | conflict |
| PDB | External Database | Details |
|---|---|---|
| U 3466 | A 13466 | conflict |
| A 3468 | C 13468 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 47 | Gly 47 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Uy1 3550 | U 5943 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Aac 2 | Gly 2 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Lys 24 | Asn 24 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 86 |
| Total formula weight | 4056087.3 | |
| Non-Polymers* | Number of molecules | 790 |
| Total formula weight | 15695.8 | |
| All* | Total formula weight | 4071783.0 |
