7O7J
Crystal structure of the human HIPK3 kinase domain bound to abemaciclib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Homeodomain-interacting protein kinase 3 | polymer | 404 | 46144.8 | 1 | UniProt (Q9H422) Pfam (PF00069) | Homo sapiens (Human) | Androgen receptor-interacting nuclear protein kinase,ANPK,Fas-interacting serine/threonine-protein kinase,FIST,Homolog of protein kinase YAK1 |
| 2 | B (A) | N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine | non-polymer | 506.6 | 1 | Chemie (6ZV) | |||
| 3 | C (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46144.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.6 | |
| All* | Total formula weight | 46651.4 |
