7O5C
14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-159
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
2 | P | Transcription factor p65 | polymer | 13 | 1412.4 | 1 | UniProt (Q04206) In PDB | Homo sapiens | Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 |
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | A | 4-methanoyl-~{N}-(1-methylpyrazol-3-yl)benzamide | non-polymer | 229.2 | 1 | Chemie (V2T) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
P: 39 - 51 (UniProt: Q04206)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Arg 49 | Glu 49 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27971.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 356.8 | |
All* | Total formula weight | 28328.1 |