7O50
Crystal structure of human legumain in complex with Gly-Ser-Asn peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Legumain | polymer | 262 | 29944.6 | 2 | UniProt (Q99538) Pfam (PF01650) | Homo sapiens (Human) | Asparaginyl endopeptidase,Protease,cysteine 1 |
| 2 | C, D (H, C) | GLY-SER-ASN | polymer | 4 | 302.3 | 2 | synthetic construct | ||
| 3 | E, F, G (G, J, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | J, K, L, M (A, B, H, C) | water | water | 18.0 | 427 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 287 (UniProt: Q99538)
| PDB | External Database | Details |
|---|---|---|
| Snn 147 | Asp 147 | conflict |
| Gln 263 | Asn 263 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60493.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 62209.3 |
