7O50
Crystal structure of human legumain in complex with Gly-Ser-Asn peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Legumain | polymer | 262 | 29944.6 | 2 | UniProt (Q99538) Pfam (PF01650) In PDB | Homo sapiens (Human) | Asparaginyl endopeptidase,Protease,cysteine 1 |
2 | H, C | GLY-SER-ASN | polymer | 4 | 302.3 | 2 | synthetic construct | ||
3 | G, J, P | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | water | water | 18.0 | 427 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 287 (UniProt: Q99538)
PDB | External Database | Details |
---|---|---|
Snn 147 | Asp 147 | conflict |
Gln 263 | Asn 263 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 60493.7 | |
Branched | Number of molecules | 3 |
Total formula weight | 1273.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 62209.3 |