7O48
Crystal structure of carbonic anhydrase from schistosoma mansoni with 4-(2-(3-(4-iodophenyl)thioureido)ethyl)benzenesulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Carbonic anhydrase | polymer | 312 | 35704.9 | 2 | UniProt (A0A3Q0KSG2) Pfam (PF00194) In PDB | Schistosoma mansoni (Blood fluke) | |
2 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B, G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | A, B | 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]thiourea | non-polymer | 461.3 | 2 | Chemie (TKE) | |||
7 | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 298 (UniProt: A0A3Q0KSG2)
PDB | External Database | Details |
---|---|---|
Asp 12 | - | expression tag |
Ala 13 | - | expression tag |
Ala 14 | - | expression tag |
Gln 15 | - | expression tag |
Pro 16 | - | expression tag |
Ala 17 | - | expression tag |
Arg 18 | - | expression tag |
Arg 19 | - | expression tag |
Ala 20 | - | expression tag |
Arg 299 | - | expression tag |
Gly 300 | - | expression tag |
Gly 301 | - | expression tag |
Pro 302 | - | expression tag |
Glu 303 | - | expression tag |
Gln 304 | - | expression tag |
Lys 305 | - | expression tag |
Leu 306 | - | expression tag |
Ile 307 | - | expression tag |
Ser 308 | - | expression tag |
Glu 309 | - | expression tag |
Glu 310 | - | expression tag |
Asp 311 | - | expression tag |
Leu 312 | - | expression tag |
Asn 313 | - | expression tag |
Ser 314 | - | expression tag |
Ala 315 | - | expression tag |
Val 316 | - | expression tag |
Asp 317 | - | expression tag |
His 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
His 322 | - | expression tag |
His 323 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 71409.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2030.4 | |
All* | Total formula weight | 73864.6 |