7O2R
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ITF3985
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone deacetylase 6 | polymer | 365 | 40342.5 | 1 | UniProt (F8W4B7) Pfam (PF00850) | Danio rerio (Zebrafish Brachydanio rerio) | |
| 2 | B (A) | 3,5-bis(fluoranyl)-~{N}-oxidanyl-4-[(5-pyrimidin-2-yl-1,2,3,4-tetrazol-2-yl)methyl]benzamide | non-polymer | 333.3 | 1 | Chemie (V05) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E, F, G, H... (A) | IODIDE ION | non-polymer | 126.9 | 6 | Chemie (IOD) | |||
| 5 | J, K (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | L (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | M (A) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: F8W4B7)
| PDB | External Database | Details |
|---|---|---|
| Gly 434 | - | cloning artifact |
| Ser 435 | - | cloning artifact |
| Asn 436 | - | cloning artifact |
| Ala 437 | - | cloning artifact |
| Gly 438 | - | cloning artifact |
| Gly 439 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40342.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1344.4 | |
| All* | Total formula weight | 41686.9 |
