7O1K
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A, beta-C92A mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 3-hydroxyacyl-CoA dehydrogenase | polymer | 736 | 77947.8 | 2 | UniProt (O53872) Pfam (PF00378) Pfam (PF02737) Pfam (PF00725) In PDB | Mycobacterium tuberculosis H37Rv | |
2 | C, D | Putative acyltransferase Rv0859 | polymer | 403 | 42428.3 | 2 | UniProt (O53871) Pfam (PF00108) Pfam (PF02803) In PDB | Mycobacterium tuberculosis H37Rv | |
3 | A, D, B, C | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
4 | C, A, D, B | SULFATE ION | non-polymer | 96.1 | 28 | Chemie (SO4) | |||
5 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 720 (UniProt: O53872)
C, D: 1 - 403 (UniProt: O53871)
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
Gly -14 | - | expression tag |
Ser -13 | - | expression tag |
Ser -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Ser -5 | - | expression tag |
Gln -4 | - | expression tag |
Asp -3 | - | expression tag |
Pro -2 | - | expression tag |
Asn -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 141 | Glu 141 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 240752.1 | |
Non-Polymers* | Number of molecules | 36 |
Total formula weight | 3426.5 | |
All* | Total formula weight | 244178.6 |