7O1I
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D | Putative acyltransferase Rv0859 | polymer | 403 | 42476.4 | 1 | UniProt (O53871) Pfam (PF00108) Pfam (PF02803) In PDB | Mycobacterium tuberculosis H37Rv | |
2 | A | 3-hydroxyacyl-CoA dehydrogenase | polymer | 736 | 77947.8 | 1 | UniProt (O53872) Pfam (PF00378) Pfam (PF02737) Pfam (PF00725) In PDB | Mycobacterium tuberculosis H37Rv | |
3 | D | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
4 | D, A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | D, A | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
6 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A: 1 - 720 (UniProt: O53872)
PDB | External Database | Details |
---|---|---|
Met -11 | - | initiating methionine |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -5 | - | expression tag |
His -5 | - | expression tag |
His -5 | - | expression tag |
Ser -5 | - | expression tag |
Gln -5 | - | expression tag |
Asp -5 | - | expression tag |
Pro -5 | - | expression tag |
Asn -5 | - | expression tag |
Ser -5 | - | expression tag |
Ala 141 | Glu 141 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 120424.1 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1912.4 | |
All* | Total formula weight | 122336.5 |