7NZY
Crystal structure of human Casein Kinase I delta in complex with CGS-15943
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Casein kinase I isoform delta | polymer | 314 | 36457.9 | 4 | UniProt (P48730) Pfam (PF00069) In PDB | Homo sapiens (Human) | CKI-delta,CKId,Tau-protein kinase CSNK1D |
2 | A, B, C, D | 9-chloranyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine | non-polymer | 285.7 | 4 | Chemie (UX2) | |||
3 | A, D | MALONATE ION | non-polymer | 102.0 | 4 | Chemie (MLI) | |||
4 | B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
5 | water | water | 18.0 | 663 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 294 (UniProt: P48730)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 145831.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1930.8 | |
All* | Total formula weight | 147762.3 |