7NZB

Mutant V517L of the SH3 domain of JNK-interacting protein 1 (JIP1)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB, CCC, DDD, EEE...	SH3 domain of JNK-interacting protein 1 (JIP1)	polymer	63	7540.4	12	UniProt (Q9UQF2) Pfam (PF14604) In PDB	Homo sapiens (Human)	JIP-1,JNK-interacting protein 1,Islet-brain 1,IB-1,JNK MAP kinase scaffold protein 1,Mitogen-activated protein kinase 8-interacting protein 1,C-Jun-amino-terminal kinase-interacting protein 1
2	AAA	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	BBB, DDD, FFF, KKK	TETRAETHYLENE GLYCOL	non-polymer		194.2	4	Chemie (PG4)
4		water	water		18.0	574	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH, III, JJJ, KKK, LLL: 490 - 549 (UniProt: Q9UQF2)

PDB	External Database	Details
Gly 487	-	expression tag
His 488	-	expression tag
Met 489	-	expression tag
Leu 517	Val 517	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	90484.7
Non-Polymers*	Number of molecules	5
	Total formula weight	871.9
All*	Total formula weight	91356.6

*Water molecules are not included.