7NYO

Mutant A541L of SH3 domain of JNK-interacting Protein 1 (JIP1)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB, CCC, DDD	SH3 domain of JNK-interacting Protein 1 (JIP1)	polymer	63	7568.4	4	UniProt (Q9UQF2) Pfam (PF14604) In PDB	Homo sapiens (Human)	JIP-1,JNK-interacting protein 1,Islet-brain 1,IB-1,JNK MAP kinase scaffold protein 1,Mitogen-activated protein kinase 8-interacting protein 1,C-Jun-amino-terminal kinase-interacting protein 1
2	AAA, CCC	TETRAETHYLENE GLYCOL	non-polymer		194.2	3	Chemie (PG4)
3	BBB	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	DDD	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5		water	water		18.0	525	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC, DDD: 490 - 549 (UniProt: Q9UQF2)

PDB	External Database	Details
Gly 487	-	expression tag
His 488	-	expression tag
Met 489	-	expression tag
Leu 541	Ala 541	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	30273.8
Non-Polymers*	Number of molecules	5
	Total formula weight	740.8
All*	Total formula weight	31014.6

*Water molecules are not included.