7NWV
Structure of recombinant human beta-glucocerebrosidase in complex with BODIPY Tagged Cyclophellitol activity based probe
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB | Lysosomal acid glucosylceramidase | polymer | 497 | 55659.2 | 2 | UniProt (P04062) Pfam (PF02055) Pfam (PF17189) In PDB | Homo sapiens (Human) | Lysosomal acid GCase,Acid beta-glucosidase,Alglucerase,Beta-glucocerebrosidase,Beta-GC,Cholesterol glucosyltransferase,SGTase,Cholesteryl-beta-glucosidase,D-glucosyl-N-acylsphingosine glucohydrolase,Imiglucerase |
2 | AdA, BdB | 1-deoxy-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G62182OO) | |||
3 | AAA, BBB | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
4 | AAA, BBB | (1~{S},2~{R},3~{R},4~{S},5~{S})-4-[[4-[4-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaen-8-yl]butyl]-1,2,3-triazol-1-yl]methyl]cyclohexane-1,2,3,5-tetrol | non-polymer | 531.4 | 2 | Chemie (UUH) | |||
5 | AAA, BBB | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
6 | AAA, BBB | 1,2-ETHANEDIOL | non-polymer | 62.1 | 35 | Chemie (EDO) | |||
7 | AAA | 8-[4-(1-ethyl-1,2,3-triazol-4-yl)butyl]-2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaene | non-polymer | 399.3 | 1 | Chemie (UUE) | |||
8 | water | water | 18.0 | 744 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 111318.4 | |
Branched | Number of molecules | 2 |
Total formula weight | 1141.1 | |
Non-Polymers* | Number of molecules | 49 |
Total formula weight | 5066.6 | |
All* | Total formula weight | 117526.1 |