7NWG
Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 51 | 28S Ribosomal RNA | polymer | 3788 | 1226619.4 | 1 | Oryctolagus cuniculus | ||
2 | 71 | 5S Ribosomal RNA | polymer | 120 | 38691.9 | 1 | GenBank (4CXE_4) | Oryctolagus cuniculus | |
3 | 81 | 5.8S Ribosomal RNA | polymer | 151 | 48545.7 | 1 | Oryctolagus cuniculus | ||
4 | A2 | 18S Ribosomal RNA | polymer | 1818 | 586374.9 | 1 | Oryctolagus cuniculus | ||
5 | B2 | 40S ribosomal protein SA | polymer | 295 | 32958.0 | 1 | UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB | Oryctolagus cuniculus (Rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
6 | C2 | 40S ribosomal protein S3a | polymer | 264 | 29942.0 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | |
7 | D2 | 40S ribosomal protein S2 | polymer | 259 | 27995.7 | 1 | Oryctolagus cuniculus (Bovine) | ||
8 | E2 | 40S ribosomal protein S3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | |
9 | F2 | S4 | polymer | 262 | 29523.7 | 1 | Oryctolagus cuniculus | ||
10 | G2 | Ribosomal protein S5 | polymer | 205 | 23044.7 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | |
11 | H2 | 40S ribosomal protein S6 | polymer | 262 | 30070.4 | 1 | UniProt (A0A5K1UJS7) Pfam (PF01092) In PDB | Oryctolagus cuniculus (Rabbit) | |
12 | I2 | ribosomal protein eS7 | polymer | 190 | 21716.4 | 1 | UniProt (G1SVB0) Pfam (PF01251) In PDB | Oryctolagus cuniculus (Rabbit) | |
13 | J2 | 40S ribosomal protein S8 | polymer | 206 | 24003.0 | 1 | UniProt (G1TJW1) Pfam (PF01201) In PDB | Oryctolagus cuniculus (Rabbit) | |
14 | K2 | 40S ribosomal protein S9 | polymer | 194 | 22655.6 | 1 | UniProt (A0A1S3APZ1) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | |
15 | L2 | 40S ribosomal protein S10 | polymer | 151 | 17422.1 | 1 | UniProt (A0A2F0BDG8) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
16 | M2 | 40S ribosomal protein S11 | polymer | 158 | 18513.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | |
17 | N2 | 40S ribosomal protein S12 | polymer | 123 | 13709.1 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
18 | O2 | ribosomal protein uS15 | polymer | 149 | 17057.1 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (Rabbit) | |
19 | P2 | uS11 | polymer | 168 | 18134.0 | 1 | UniProt (G1T1F0) Pfam (PF00411) In PDB | Oryctolagus cuniculus (Rabbit) | |
20 | Q2 | 40S ribosomal protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | |
21 | R2 | Ribosomal protein S16 | polymer | 157 | 17585.7 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | |
22 | S2 | 40S ribosomal protein S17 | polymer | 145 | 16782.6 | 1 | UniProt (S7Q348) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
23 | T2 | 40S ribosomal protein uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
24 | U2 | S19 | polymer | 145 | 16106.6 | 1 | UniProt (G1TN62) Pfam (PF01090) In PDB | Oryctolagus cuniculus (Rabbit) | |
25 | V2 | 40S ribosomal protein S20 | polymer | 130 | 14603.1 | 1 | Oryctolagus cuniculus | ||
26 | W2 | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (Q32PB8) Pfam (PF01249) In PDB | Oryctolagus cuniculus | |
27 | X2 | Ribosomal protein S15a | polymer | 139 | 15778.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
28 | Y2 | Ribosomal protein S23 | polymer | 141 | 15626.4 | 1 | UniProt (G1SZ47) Pfam (PF00164) In PDB | Oryctolagus cuniculus (Rabbit) | |
29 | Z2 | 40S ribosomal protein S24 | polymer | 146 | 17007.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
30 | a2 | ribosomal protein eS25 | polymer | 198 | 22090.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
31 | b2 | 40S ribosomal protein S26 | polymer | 117 | 13147.6 | 1 | UniProt (T0M5X4) Pfam (PF01283) In PDB | Oryctolagus cuniculus (Rabbit) | |
32 | c2 | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | |
33 | d2 | 40S ribosomal protein S28 | polymer | 69 | 7836.0 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | |
34 | e2 | uS14 | polymer | 55 | 6559.6 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (Rabbit) | |
35 | f2 | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | |
36 | g2 | eS31 | polymer | 68 | 7986.4 | 1 | UniProt (G1SK22) Pfam (PF01599) In PDB | Oryctolagus cuniculus (Rabbit) | |
37 | h2 | ribosomal protein RACK1 | polymer | 313 | 34669.1 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
38 | A3 | L8 | polymer | 246 | 26840.5 | 1 | Oryctolagus cuniculus | ||
39 | B3 | uL3 | polymer | 403 | 46108.0 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (Rabbit) | |
40 | C3 | uL4 | polymer | 425 | 47727.6 | 1 | UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374) In PDB | Oryctolagus cuniculus (Rabbit) | |
41 | D3 | 60S ribosomal protein L5 | polymer | 297 | 34481.8 | 1 | UniProt (G1SYJ6) Pfam (PF17144) Pfam (PF14204) In PDB | Oryctolagus cuniculus (Rabbit) | |
42 | E3 | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB | Oryctolagus cuniculus (Rabbit) | |
43 | F3 | uL30 | polymer | 249 | 29514.3 | 1 | UniProt (G1SV32) Pfam (PF08079) Pfam (PF00327) In PDB | Oryctolagus cuniculus (Rabbit) | |
44 | G3 | L7a | polymer | 241 | 27480.6 | 1 | UniProt (G1STW0) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
45 | H3 | L9 | polymer | 190 | 21627.2 | 1 | UniProt (G1SWI6) Pfam (PF00347) In PDB | Oryctolagus cuniculus (Rabbit) | |
46 | I3 | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L10 (Predicted) |
47 | J3 | 60S ribosomal protein L11 | polymer | 181 | 20670.9 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (Rabbit) | |
48 | L3 | L13 | polymer | 211 | 24331.7 | 1 | UniProt (G1TKB3) Pfam (PF01294) In PDB | Oryctolagus cuniculus (Rabbit) | |
49 | M3 | Ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) In PDB | Oryctolagus cuniculus (Rabbit) | |
50 | N3 | Ribosomal protein L15 | polymer | 203 | 24076.1 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (Rabbit) | |
51 | O3 | 60S RIBOSOMAL PROTEIN UL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus | ||
52 | P3 | uL22 | polymer | 199 | 23056.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
53 | Q3 | L18 | polymer | 188 | 21699.7 | 1 | Oryctolagus cuniculus | ||
54 | R3 | 60S ribosomal protein L19 | polymer | 196 | 23535.3 | 1 | UniProt (Q3T0W9) Pfam (PF01280) In PDB | Oryctolagus cuniculus (Rabbit) | |
55 | S3 | 60S ribosomal protein L18a | polymer | 176 | 20827.6 | 1 | UniProt (A0A287APR1) Pfam (PF01775) In PDB | Oryctolagus cuniculus | |
56 | T3 | eL21 | polymer | 159 | 18478.8 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (Rabbit) | |
57 | U3 | L22 | polymer | 128 | 14799.0 | 1 | Oryctolagus cuniculus | ||
58 | V3 | eL14 | polymer | 131 | 13972.4 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (Rabbit) | |
59 | X3 | uL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (Rabbit) | |
60 | Y3 | Ribosomal protein L26 | polymer | 132 | 15705.6 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (Rabbit) | |
61 | Z3 | 60S ribosomal protein L27 | polymer | 135 | 15704.6 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (Rabbit) | |
62 | a3 | uL15 | polymer | 160 | 17831.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
63 | b3 | eL29 | polymer | 245 | 26708.7 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (Rabbit) | |
64 | c3 | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
65 | d3 | eL31 | polymer | 107 | 12635.7 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (Rabbit) | |
66 | e3 | eL32 | polymer | 128 | 15022.0 | 1 | UniProt (G1TUN8) Pfam (PF01655) In PDB | Oryctolagus cuniculus (Rabbit) | |
67 | f3 | eL33 | polymer | 109 | 12449.6 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (Rabbit) | |
68 | g3 | 60S ribosomal protein L34 | polymer | 126 | 14210.1 | 1 | UniProt (G1U945) Pfam (PF01199) In PDB | Oryctolagus cuniculus (Rabbit) | |
69 | h3 | uL29 | polymer | 122 | 14435.4 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (Rabbit) | |
70 | i3 | 60S ribosomal protein L36 | polymer | 117 | 13546.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
71 | j3 | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) In PDB | Oryctolagus cuniculus (Rabbit) | |
72 | k3 | L38 | polymer | 69 | 8107.8 | 1 | Oryctolagus cuniculus | ||
73 | l3 | eL39 | polymer | 50 | 6324.6 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (Rabbit) | |
74 | m3 | 60S RIBOSOMAL PROTEIN EL40 | polymer | 128 | 14695.3 | 1 | Oryctolagus cuniculus | ||
75 | n3 | 60s ribosomal protein l41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) In PDB | Oryctolagus cuniculus (Rabbit) | eL41 |
76 | o3 | eL42 | polymer | 142 | 16170.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
77 | p3 | ribosomal protein eL43 | polymer | 109 | 12010.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
78 | r3 | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) In PDB | Oryctolagus cuniculus (Rabbit) | |
79 | q3 | A/P-Site tRNA | polymer | 74 | 23825.2 | 1 | Oryctolagus cuniculus | ||
80 | t3 | 60S acidic ribosomal protein P0 | polymer | 318 | 34380.5 | 1 | UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) In PDB | Oryctolagus cuniculus (Rabbit) | |
81 | u3 | uL12 | polymer | 195 | 21295.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
82 | v3 | mRNA | polymer | 18 | 5719.4 | 1 | Oryctolagus cuniculus | ||
83 | 33 | P/E-Site tRNA | polymer | 75 | 24118.3 | 1 | Oryctolagus cuniculus | ||
84 | w3 | Ribosomal protein | polymer | 217 | 24879.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) In PDB | Oryctolagus cuniculus (Rabbit) | |
85 | 1 | Sec61Beta | polymer | 15 | 1788.0 | 1 | Oryctolagus cuniculus | ||
86 | W | 60S ribosomal protein L24-like protein | polymer | 134 | 15538.3 | 1 | UniProt (A0A061I3X8) Pfam (PF01246) In PDB | Oryctolagus cuniculus (Rabbit) | |
87 | 51, 81, A2, 33, F2... | MAGNESIUM ION | non-polymer | 24.3 | 299 | Chemie (MG) | |||
88 | 51 | BLASTICIDIN S | non-polymer | 422.4 | 1 | Chemie (BLS) | |||
89 | m3, o3, A2, p3, b2... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
B2: 1 - 295 (UniProt: G1TLT8)
C2: 1 - 264 (UniProt: G1SS70)
G2: 1 - 204 (UniProt: G1TFM5)
H2: 1 - 249 (UniProt: A0A5K1UJS7)
J2: 2 - 207 (UniProt: G1TJW1)
M2: 1 - 158 (UniProt: G1TRM4)
P2: -4 - 151 (UniProt: G1T1F0)
R2: -10 - 146 (UniProt: G1SGX4)
U2: 1 - 145 (UniProt: G1TN62)
d2: 1 - 69 (UniProt: G1TIB4)
B3: 2 - 403 (UniProt: G1TL06)
C3: 1 - 378 (UniProt: G1SVW5)
D3: 2 - 297 (UniProt: G1SYJ6)
G3: 79 - 319 (UniProt: G1STW0)
J3: -2 - 178 (UniProt: G1TUB8)
L3: 1 - 211 (UniProt: G1TKB3)
b3: 1 - 226 (UniProt: G1SGR6)
PDB | External Database | Details |
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Thr 114 | Ala 114 | conflict |
PDB | External Database | Details |
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Gly 236 | Ser 236 | conflict |
Ala 242 | Thr 242 | conflict |
PDB | External Database | Details |
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Met 0 | - | initiating methionine |
PDB | External Database | Details |
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Leu -12 | - | expression tag |
Phe -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ala -8 | - | expression tag |
Ser -7 | - | expression tag |
Glu -6 | - | expression tag |
Ala -5 | - | expression tag |
Val -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Lys 0 | - | expression tag |
PDB | External Database | Details |
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Arg 47 | Gly 47 | variant |
PDB | External Database | Details |
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Gln 25 | Leu 25 | conflict |
Ser 29 | Gly 29 | conflict |
PDB | External Database | Details |
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Met -16 | - | initiating methionine |
Lys -15 | - | expression tag |
Ala -14 | - | expression tag |
Arg -13 | - | expression tag |
Ala -12 | - | expression tag |
Leu -11 | - | expression tag |
Ser -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Val -6 | - | expression tag |
Arg -5 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Val -8 | Glu 18 | conflict |
Glu -7 | Asp 19 | conflict |
Leu -6 | Arg 20 | conflict |
Val -5 | His 21 | conflict |
Leu -4 | Ser 22 | conflict |
Val -3 | Ser 23 | conflict |
Leu -2 | Ala 24 | conflict |
Gly -1 | Ala 25 | conflict |
PDB | External Database | Details |
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Gly 119 | Trp 119 | conflict |
PDB | External Database | Details |
---|---|---|
His 5 | Arg 5 | conflict |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
PDB | External Database | Details |
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Val 379 | - | expression tag |
Lys 380 | - | expression tag |
Lys 381 | - | expression tag |
Pro 382 | - | expression tag |
Arg 383 | - | expression tag |
Ala 384 | - | expression tag |
Val 385 | - | expression tag |
Gly 386 | - | expression tag |
Ile 387 | - | expression tag |
Lys 388 | - | expression tag |
Gln 389 | - | expression tag |
Lys 390 | - | expression tag |
Lys 391 | - | expression tag |
Lys 392 | - | expression tag |
Pro 393 | - | expression tag |
Val 394 | - | expression tag |
Val 395 | - | expression tag |
Gly 396 | - | expression tag |
Arg 397 | - | expression tag |
Lys 398 | - | expression tag |
Ala 399 | - | expression tag |
Ala 400 | - | expression tag |
Ala 401 | - | expression tag |
Ala 402 | - | expression tag |
Lys 403 | - | expression tag |
Lys 404 | - | expression tag |
Pro 405 | - | expression tag |
Ala 406 | - | expression tag |
Ala 407 | - | expression tag |
Asp 408 | - | expression tag |
Lys 409 | - | expression tag |
Lys 410 | - | expression tag |
Ala 411 | - | expression tag |
Ala 412 | - | expression tag |
Asp 413 | - | expression tag |
Lys 414 | - | expression tag |
Arg 415 | - | expression tag |
Ala 416 | - | expression tag |
Gly 417 | - | expression tag |
Pro 418 | - | expression tag |
Glu 419 | - | expression tag |
Asp 420 | - | expression tag |
Lys 421 | - | expression tag |
Lys 422 | - | expression tag |
Pro 423 | - | expression tag |
Ala 424 | - | expression tag |
Ala 425 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
PDB | External Database | Details |
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Gly 244 | Cys 167 | conflict |
PDB | External Database | Details |
---|---|---|
Gln 0 | - | insertion |
Arg 1 | - | insertion |
Pro 2 | - | insertion |
PDB | External Database | Details |
---|---|---|
Arg 74 | His 74 | conflict |
Arg 190 | His 190 | conflict |
PDB | External Database | Details |
---|---|---|
Ala 227 | - | expression tag |
Pro 228 | - | expression tag |
Val 229 | - | expression tag |
Pro 230 | - | expression tag |
Ala 231 | - | expression tag |
Gln 232 | - | expression tag |
Ala 233 | - | expression tag |
Pro 234 | - | expression tag |
Pro 235 | - | expression tag |
Lys 236 | - | expression tag |
Gly 237 | - | expression tag |
Ala 238 | - | expression tag |
Gln 239 | - | expression tag |
Pro 240 | - | expression tag |
Pro 241 | - | expression tag |
Ala 242 | - | expression tag |
Lys 243 | - | expression tag |
Ala 244 | - | expression tag |
Pro 245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 86 |
Total formula weight | 3504164.6 | |
Non-Polymers* | Number of molecules | 308 |
Total formula weight | 8212.9 | |
All* | Total formula weight | 3512377.6 |