7NVO
Human TRiC complex in open state with nanobody bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, e | T-complex protein 1 subunit epsilon | polymer | 541 | 59750.0 | 2 | UniProt (P48643) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-epsilon,CCT-epsilon |
2 | H, h | T-complex protein 1 subunit eta | polymer | 543 | 59443.5 | 2 | UniProt (Q99832) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
3 | Q, q | T-complex protein 1 subunit theta | polymer | 548 | 59691.4 | 2 | UniProt (P50990) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15 |
4 | Z, z | T-complex protein 1 subunit zeta | polymer | 531 | 58106.1 | 2 | UniProt (P40227) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
5 | G, g | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 2 | UniProt (P49368) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
6 | A, a | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 2 | UniProt (P17987) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-alpha,CCT-alpha |
7 | D, d | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 2 | UniProt (P50991) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
8 | B, b | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 2 | UniProt (P78371) Pfam (PF00118) In PDB | Homo sapiens (Human) | TCP-1-beta,CCT-beta |
9 | N, n | Nanobody | polymer | 129 | 14412.8 | 2 | Lama glama | ||
10 | g, Z, a, G, d... | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
11 | Z, a, G, A, d... | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 16 | Chemie (ADP) | |||
12 | g, Z, a, G, A... | ALUMINUM FLUORIDE | non-polymer | 84.0 | 12 | Chemie (AF3) | |||
13 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 18 |
Total formula weight | 975998.8 | |
Non-Polymers* | Number of molecules | 44 |
Total formula weight | 8231.8 | |
All* | Total formula weight | 984230.6 |