7NVO
Human TRiC complex in open state with nanobody bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (E, e) | T-complex protein 1 subunit epsilon | polymer | 541 | 59750.0 | 2 | UniProt (P48643) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-epsilon,CCT-epsilon |
| 2 | B, K (H, h) | T-complex protein 1 subunit eta | polymer | 543 | 59443.5 | 2 | UniProt (Q99832) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
| 3 | C, L (Q, q) | T-complex protein 1 subunit theta | polymer | 548 | 59691.4 | 2 | UniProt (P50990) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15 |
| 4 | D, M (Z, z) | T-complex protein 1 subunit zeta | polymer | 531 | 58106.1 | 2 | UniProt (P40227) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
| 5 | E, N (G, g) | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 2 | UniProt (P49368) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
| 6 | F, O (A, a) | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 2 | UniProt (P17987) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-alpha,CCT-alpha |
| 7 | G, P (D, d) | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 2 | UniProt (P50991) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
| 8 | H, Q (B, b) | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 2 | UniProt (P78371) Pfam (PF00118) | Homo sapiens (Human) | TCP-1-beta,CCT-beta |
| 9 | I, R (N, n) | Nanobody | polymer | 129 | 14412.8 | 2 | Lama glama | ||
| 10 | AB, BA, DB, EA, FB... (g, Z, a, G, d...) | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
| 11 | AA, CB, DA, GA, GB... (Z, a, G, A, d...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 16 | Chemie (ADP) | |||
| 12 | BB, CA, EB, FA, IA... (g, Z, a, G, A...) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 12 | Chemie (AF3) | |||
| 13 | KB, LB, MB, NB, OB... (E, H, Q, D, e...) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 975998.8 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 8231.8 | |
| All* | Total formula weight | 984230.6 |
