7NQ3
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N4-((1R,5S,6r)-3-oxabicyclo[3.1.0]hexan-6-yl)-6-((S)-methoxy(phenyl)methyl)-N2-methylpyridine-2,4-dicarboxamide
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Bromodomain-containing protein 2 | polymer | 115 | 13432.5 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
3 | AAA | 6-[(~{S})-methoxy(phenyl)methyl]-~{N}2-methyl-~{N}4-[(1~{S},5~{R})-3-oxabicyclo[3.1.0]hexan-6-yl]pyridine-2,4-dicarboxamide | non-polymer | 381.4 | 1 | Chemie (ULQ) | |||
4 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
AAA: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Gly 341 | - | expression tag |
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13432.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 567.6 | |
All* | Total formula weight | 14000.1 |