7NQ1
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 6-((S)-hydroxy(phenyl)methyl)-N2-methyl-N4-((1S,2S)-2-methylcyclopropyl)pyridine-2,4-dicarboxamide
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Bromodomain-containing protein 2 | polymer | 115 | 13432.5 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
3 | AAA | ~{N}2-methyl-~{N}4-[(1~{S},2~{S})-2-methylcyclopropyl]-6-[(~{S})-oxidanyl(phenyl)methyl]pyridine-2,4-dicarboxamide | non-polymer | 339.4 | 1 | Chemie (ULK) | |||
4 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
AAA: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Gly 341 | - | expression tag |
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13432.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 525.6 | |
All* | Total formula weight | 13958.1 |