7NPX
Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 3-(3-Methoxyquinoxalin-2-yl)propanoic acid at 24 hours of soaking
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thioredoxin glutathione reductase | polymer | 598 | 65108.0 | 2 | UniProt (Q962Y6) Pfam (PF00462) Pfam (PF07992) Pfam (PF02852) UniProt (by SIFTS) (A0A3Q0KFL1) | Schistosoma mansoni (Blood fluke) | |
| 2 | C, M (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, N (A, B) | 3-(3-methoxyquinoxalin-2-yl)propanoic acid | non-polymer | 232.2 | 2 | Chemie (EY7) | |||
| 4 | E, G, O, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | F, H, I, P (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 6 | J, K, L, Q (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 598 (UniProt: Q962Y6)
| PDB | External Database | Details |
|---|---|---|
| Sec 597 | Unk 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 130216.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2758.3 | |
| All* | Total formula weight | 132974.3 |
