7NPK
ALPHA-1 ANTITRYPSIN C232S COMPLEXED WITH CMPD3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-1-antitrypsin | polymer | 403 | 45466.5 | 1 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (Human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D (A) | N-((1S,2R)-1-hydroxy-1-(o-tolyl)pentan-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxamide | non-polymer | 354.4 | 1 | Chemie (UL2) | |||
| 4 | E (A) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 2 - 393 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Arg -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Thr 1 | - | expression tag |
| Ser 232 | Cys 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45466.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 538.6 | |
| All* | Total formula weight | 46005.1 |
