7NPG
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 22
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | Amot-p130 phosphopeptide (pS175) | polymer | 20 | 2242.5 | 1 | UniProt (Q4VCS5) | Homo sapiens | Angiomotin |
| 3 | C (A) | 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide | non-polymer | 311.4 | 1 | Chemie (K92) | |||
| 4 | D, E (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | H, I (A, P) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30469.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 451.3 | |
| All* | Total formula weight | 30920.3 |
