7NNJ
Crystal Structure of NUDT4 (Diphosphoinositol polyphosphate phosphohydrolase 2) in complex with 4-O-Bn-1-PCP-InsP4 (AMR2105)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Diphosphoinositol polyphosphate phosphohydrolase 2 | polymer | 140 | 16188.4 | 2 | UniProt (Q9NZJ9) Pfam (PF00293) In PDB | Homo sapiens (Human) | DIPP-2,Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2,Nucleoside diphosphate-linked moiety X motif 4,Nudix motif 4 |
| 2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | A, B | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
| 4 | B | [oxidanyl-[(2S,3R,5S,6S)-4-phenylmethoxy-2,3,5,6-tetraphosphonooxy-cyclohexyl]oxy-phosphoryl]methylphosphonic acid | non-polymer | 748.2 | 1 | Chemie (UJN) | |||
| 5 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 146 (UniProt: Q9NZJ9)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | - | expression tag |
| Met 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32376.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1164.5 | |
| All* | Total formula weight | 33541.3 |
