7NKS

Structure of the Hantaan virus Gn glycoprotein ectodomain in complex with Fab HTN-Gn1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F (B, A)	Envelope polyprotein	polymer	365	40350.9	2	UniProt (A0A077D153) Pfam (PF01567)	Hantaan orthohantavirus	M polyprotein
2	B, D (C, H)	Fab HTN-Gn1 heavy chain	polymer	231	24284.3	2		Oryctolagus cuniculus
3	C, E (D, L)	Fab HTN-Gn1 light chain	polymer	217	22943.2	2		Oryctolagus cuniculus
4	G (G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
5	H (F)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G07617FP)
6	I, K, L (B, C)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	J (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

B, A: 18 - 371 (UniProt: A0A077D153)

PDB	External Database	Details
Thr 16	-	cloning artifact
Gly 17	-	cloning artifact
Gly 372	-	expression tag
Thr 373	-	expression tag
Lys 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	175156.6
Branched	Number of molecules	2
	Total formula weight	2470.2
Non-Polymers*	Number of molecules	4
	Total formula weight	497.5
All*	Total formula weight	178124.3

*Water molecules are not included.