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7NIU

Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AIsoform 2 of Phosphatidylcholine translocator ABCB4polymer1279140835.41UniProt (P21439)
Pfam (PF00664)
Pfam (PF00005)
In PDB
Homo sapiens (Human)ATP-binding cassette sub-family B member 4,Multidrug resistance protein 3,P-glycoprotein 3
2DQA2 Fab-fragment light chainpolymer21523258.81Homo sapiens
3EQA2 Fab-fragment heavy chainpolymer23424817.71Homo sapiens
4B4B1 Fab-fragment light chainpolymer21523347.01Homo sapiens
5C4B1 Fab-fragment heavy chainpolymer24125754.61Homo sapiens
6ACHOLESTEROLnon-polymer386.72Chemie (CLR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight238013.4
Non-Polymers*Number of molecules2
Total formula weight773.3
All*Total formula weight238786.7
*Water molecules are not included.

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PDB entries from 2024-08-07

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