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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7NFX

Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
11SRP RNA 7SLpolymer29996828.31Homo sapiens
2528S ribosomal RNApolymer34931131535.91Oryctolagus cuniculus
375S ribosomal RNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus
485.8S ribosomal RNApolymer15650143.61GenBank (4CXE_3)Oryctolagus cuniculus
5AuL2polymer24526701.31Oryctolagus cuniculus
6BuL3polymer40346108.01UniProt (G1TL06)
Pfam (PF00297)
In PDB		Oryctolagus cuniculus (Rabbit)
7C60S ribosomal protein L4polymer41346388.91UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Oryctolagus cuniculus (Rabbit)
8D60S ribosomal protein L5polymer29734481.81UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)
In PDB		Oryctolagus cuniculus (Rabbit)
9E60S ribosomal protein L6polymer29133055.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Oryctolagus cuniculus (Rabbit)
10FuL30polymer22526662.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Oryctolagus cuniculus (Rabbit)
11G60S ribosomal protein L7apolymer31936267.61UniProt (G1STW0)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)
12H60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)
In PDB		Oryctolagus cuniculus (Rabbit)
13I60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein L10 (Predicted)
14JRibosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Oryctolagus cuniculus (Rabbit)
15L60S ribosomal protein L13polymer21024216.51UniProt (G1TPV0)
In PDB		Oryctolagus cuniculus (Rabbit)
16M60S ribosomal protein L14polymer21823810.41UniProt (U3KNW6)
Pfam (PF01929)
UniProt (by SIFTS) (G1SZ12)
In PDB		Oryctolagus cuniculus (Rabbit)
17NRibosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)
In PDB		Oryctolagus cuniculus (Rabbit)
18OuL13polymer19923248.91Oryctolagus cuniculus
19PuL22polymer15317758.71UniProt (G1TVT6)
Pfam (PF00237)
UniProt (by SIFTS) (G1SCJ6)
In PDB		Oryctolagus cuniculus (Rabbit)
20QeL18polymer18721457.41UniProt (G1TX70)
Pfam (PF17135)
In PDB		Oryctolagus cuniculus (Rabbit)
21R60S RIBOSOMAL PROTEIN EL19polymer18021613.01UniProt (Q3T0W9)
Pfam (PF01280)
In PDB		Oryctolagus cuniculus
22SeL20polymer17520696.41Oryctolagus cuniculus
23TeL21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)
In PDB		Oryctolagus cuniculus (Rabbit)
24URibosomal protein L22polymer9911481.21UniProt (G1TSG1)
Pfam (PF01776)
In PDB		Oryctolagus cuniculus (Rabbit)
25VRibosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)
In PDB		Oryctolagus cuniculus (Rabbit)
26WRibosomal protein L24polymer637512.81UniProt (G1SE28)
Pfam (PF01246)
In PDB		Oryctolagus cuniculus (Rabbit)
27XuL23polymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Oryctolagus cuniculus (Rabbit)
28YRibosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Oryctolagus cuniculus (Rabbit)
29Z60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Oryctolagus cuniculus (Rabbit)
30auL15polymer14816620.61UniProt (G1SNY0)
Pfam (PF00828)
In PDB		Oryctolagus cuniculus (Rabbit)
31b60S ribosomal protein L29polymer22324608.21UniProt (G1TN82)
Pfam (PF01779)
UniProt (by SIFTS) (G1SGR6)
In PDB		Oryctolagus cuniculus (Rabbit)
32ceL30polymer9410496.41Oryctolagus cuniculus
33deL31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)
In PDB		Oryctolagus cuniculus (Rabbit)
34eeL32polymer12815022.01UniProt (G1TUN8)
Pfam (PF01655)
In PDB		Oryctolagus cuniculus (Rabbit)
35feL33polymer11012580.81UniProt (G1SF08)
Pfam (PF01247)
In PDB		Oryctolagus cuniculus (Rabbit)
36g60S ribosomal protein L34polymer12914557.51UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)
In PDB		Oryctolagus cuniculus (Rabbit)
37huL29polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)
In PDB		Oryctolagus cuniculus (Rabbit)
38ieL36polymer10412132.61Oryctolagus cuniculus
39jRibosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)
In PDB		Oryctolagus cuniculus (Rabbit)
40keL38polymer698107.81Oryctolagus cuniculus
41leL39polymer516426.81UniProt (G1SYU7)
Pfam (PF00832)
In PDB		Oryctolagus cuniculus (Rabbit)
42m60S RIBOSOMAL PROTEIN EL40polymer526199.61UniProt (P63048)
Pfam (PF01020)
In PDB		Oryctolagus cuniculus
43n60s ribosomal protein l41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
In PDB		Oryctolagus cuniculus (Rabbit)eL41
44oeL42polymer10512329.81UniProt (A0A5F9D391)
Pfam (PF00935)
In PDB		Oryctolagus cuniculus (Rabbit)
45peL43polymer9210299.41UniProt (G1SY53)
Pfam (PF01780)
In PDB		Oryctolagus cuniculus (Rabbit)
46qSignal recognition particle 19 kDa proteinpolymer14416183.71UniProt (P09132)
Pfam (PF01922)
In PDB		Homo sapiens (Human)SRP19
47reL28polymer13715783.61UniProt (G1U7L1)
Pfam (PF01778)
In PDB		Oryctolagus cuniculus (Rabbit)
48sSignal Sequencepolymer211805.21Homo sapiens
49tSignal recognition particle 14 kDa proteinpolymer13614596.01UniProt (P37108)
Pfam (PF02290)
In PDB		Homo sapiens (Human)SRP14,18 kDa Alu RNA-binding protein
50uSignal recognition particle subunit SRP68polymer62770831.61UniProt (Q9UHB9)
Pfam (PF16969)
In PDB		Homo sapiens (Human)SRP68,Signal recognition particle 68 kDa protein
51vSignal recognition particle receptor subunit betapolymer27129737.21UniProt (Q9Y5M8)
Pfam (PF09439)
In PDB		Homo sapiens (Human)SR-beta,Protein APMCF1
52wSignal recognition particle 9 kDa proteinpolymer8610127.81UniProt (P49458)
Pfam (PF05486)
In PDB		Homo sapiens (Human)SRP9
53xSignal recognition particle 54 kDa proteinpolymer50455847.71UniProt (P61011)
Pfam (PF02881)
Pfam (PF00448)
Pfam (PF02978)
In PDB		Homo sapiens (Human)SRP54
54ySignal recognition particle receptor subunit alphapolymer63869908.11UniProt (P08240)
Pfam (PF04086)
Pfam (PF02881)
Pfam (PF00448)
In PDB		Homo sapiens (Human)SR-alpha,Docking protein alpha,DP-alpha
55zSignal recognition particle subunit SRP72polymer67174720.31UniProt (O76094)
Pfam (PF17004)
Pfam (PF13181)
Pfam (PF08492)
In PDB		Homo sapiens (Human)SRP72,Signal recognition particle 72 kDa protein
56g, j, m, o, pZINC IONnon-polymer65.45Chemie (ZN)
57v, xMAGNESIUM IONnon-polymer24.32Chemie (MG)
58vGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
59xPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
Sequence modifications
B: 2 - 403 (UniProt: G1TL06)
PDBExternal DatabaseDetails
Met 1-initiating methionine
D: 2 - 297 (UniProt: G1SYJ6)
PDBExternal DatabaseDetails
Met 1-initiating methionine
E: -5 - 284 (UniProt: G1SKF7)
PDBExternal DatabaseDetails
Arg 126Lys 133conflict
Gln 217Lys 224conflict
F: 26 - 250 (UniProt: G1SV32)
PDBExternal DatabaseDetails
Ala 175Thr 174conflict
Gly 185Asn 184conflict
Arg 202His 201conflict
Glu 233Gly 232conflict
L: 2 - 211 (UniProt: G1TPV0)
PDBExternal DatabaseDetails
Ala 47-insertion
Pro 48-insertion
Arg 49-insertion
Pro 50-insertion
Ala 51-insertion
Ser 52-insertion
Gly 53-insertion
Pro 54-insertion
Leu 55-insertion
Q: 2 - 188 (UniProt: G1TX70)
PDBExternal DatabaseDetails
Arg 6Leu 6conflict
Arg 14Trp 14conflict
Ile 23Met 23conflict
Tyr 24Cys 24conflict
Arg 38His 38conflict
Asn 57Lys 57conflict
Met 66Val 66conflict
Gly 74Asp 74conflict
Arg 75Pro 75conflict
Gly 77Asn 77conflict
Ser 106Thr 106conflict
Arg 110His 110conflict
Gly 117Glu 117conflict
Asp 124His 124conflict
Cys 134Arg 134conflict
Arg 150Gln 150conflict
Arg 172Gly 172conflict
Arg 184Trp 184conflict
U: 17 - 115 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32variant
Ala 36Glu 36variant
Phe 39Ser 39variant
Gly 54Arg 54variant
Val 60Ala 60variant
Arg 97His 97variant
a: 2 - 148 (UniProt: G1SNY0)
PDBExternal DatabaseDetails
Met 1-initiating methionine
x: 1 - 504 (UniProt: P61011)
PDBExternal DatabaseDetails
Glu 226Gly 226engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains55
Total formula weight2466649.5
Non-Polymers*Number of molecules9
Total formula weight1421.0
All*Total formula weight2468070.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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