7NEU
Inhibitor Complex with Thrombin Activatable Fibrinolysis Inhibitor (TAFIa)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carboxypeptidase B2 | polymer | 400 | 45963.0 | 1 | UniProt (Q96IY4) Pfam (PF02244) Pfam (PF00246) In PDB | Homo sapiens (Human) | Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI |
| 2 | A | (1R,3S)-3-(4-ammoniobutyl)-1-(4-fluoro-2-(1-methyl-1H-imidazol-5-yl)benzyl)-1,4-azaphosphinan-1-ium-3-carboxylate 4,4-dioxide | non-polymer | 440.4 | 1 | Chemie (U9K) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 2 - 401 (UniProt: Q96IY4)
| PDB | External Database | Details |
|---|---|---|
| Thr 147 | Ala 169 | conflict |
| Cys 305 | Ser 327 | conflict |
| Ile 329 | Thr 351 | conflict |
| Tyr 333 | His 355 | conflict |
| Gln 335 | His 357 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45963.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1068.8 | |
| All* | Total formula weight | 47031.8 |
