7NCF
Crystal structure of HIPK2 in complex with MU135 (compound 21e)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Homeodomain-interacting protein kinase 2 | polymer | 367 | 42446.5 | 1 | UniProt (Q9H2X6) Pfam (PF00069) | Homo sapiens (Human) | hHIPk2 |
| 2 | B (A) | 3-(4-Tert-butylphenyl)-5-(1H-pyrazol-4-yl)furo[3,2-b]pyridine | non-polymer | 317.4 | 1 | Chemie (U82) | |||
| 3 | C (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 183 - 547 (UniProt: Q9H2X6)
| PDB | External Database | Details |
|---|---|---|
| Ser 181 | - | expression tag |
| Met 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42446.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 317.4 | |
| All* | Total formula weight | 42763.9 |
