7NBH
Crystal structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB, CCC, DDD | Serine racemase | polymer | 346 | 37684.0 | 4 | UniProt (Q9GZT4) Pfam (PF00291) In PDB | Homo sapiens (Human) | D-serine ammonia-lyase,D-serine dehydratase,L-serine ammonia-lyase,L-serine dehydratase |
2 | CCC, AAA, DDD, BBB | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
3 | AAA, CCC, DDD, BBB | SODIUM ION | non-polymer | 23.0 | 9 | Chemie (NA) | |||
4 | CCC, AAA, DDD, BBB | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
5 | CCC, AAA, DDD | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
6 | AAA, DDD, BBB | N-[(1H-benzimidazol-2-yl)methyl]furan-2-carboxamide | non-polymer | 241.2 | 6 | Chemie (W0D) | |||
7 | CCC, DDD | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
8 | CCC | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
9 | DDD | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
10 | water | water | 18.0 | 975 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 340 (UniProt: Q9GZT4)
PDB | External Database | Details |
---|---|---|
Asp 2 | Cys 2 | engineered mutation |
Asp 6 | Cys 6 | engineered mutation |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 150735.9 | |
Non-Polymers* | Number of molecules | 47 |
Total formula weight | 3836.8 | |
All* | Total formula weight | 154572.8 |