7NBG
Crystal structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB, CCC, DDD | Serine racemase | polymer | 346 | 37455.9 | 4 | UniProt (Q9GZT4) Pfam (PF00291) In PDB | Homo sapiens (Human) | D-serine ammonia-lyase,D-serine dehydratase,L-serine ammonia-lyase,L-serine dehydratase |
2 | AAA, DDD, BBB, CCC | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) | |||
3 | CCC, AAA, DDD, BBB | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
4 | AAA, CCC, DDD, BBB | SODIUM ION | non-polymer | 23.0 | 9 | Chemie (NA) | |||
5 | CCC, AAA, DDD, BBB | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
6 | CCC, AAA, DDD | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
7 | AAA, BBB | ~{N}-[2-(2-methylphenyl)ethyl]ethanamide | non-polymer | 177.2 | 2 | Chemie (U78) | |||
8 | DDD, BBB | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
9 | DDD | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
10 | DDD | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
11 | DDD | ORTHO-XYLENE | non-polymer | 106.2 | 1 | Chemie (OXE) | |||
12 | water | water | 18.0 | 941 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 340 (UniProt: Q9GZT4)
PDB | External Database | Details |
---|---|---|
Asp 2 | Cys 2 | engineered mutation |
Asp 6 | Cys 6 | engineered mutation |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 149823.5 | |
Non-Polymers* | Number of molecules | 44 |
Total formula weight | 3556.9 | |
All* | Total formula weight | 153380.3 |