7NAM

LRP6_E1 in complex with Lr-EET-3.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Low-density lipoprotein receptor-related protein 6	polymer	317	35614.8	1	UniProt (O75581) Pfam (PF00058) Pfam (PF14670) In PDB	Homo sapiens (Human)	LRP-6
2	B	Trypsin inhibitor 2	polymer	32	3370.8	1		synthetic construct
3	D, E	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		878.8	2	In PDB GlyTouCan (G93904UY)
4	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	228	Chemie (HOH)

Sequence modifications

A: 20 - 326 (UniProt: O75581)

PDB	External Database	Details
Gly 18	-	expression tag
Ser 19	-	expression tag
Asn 327	-	expression tag
Ser 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38985.7
Branched	Number of molecules	2
	Total formula weight	1757.6
Non-Polymers*	Number of molecules	2
	Total formula weight	46.0
All*	Total formula weight	40789.3

*Water molecules are not included.