7N8B

Cycloheximide bound vacant 80S structure isolated from cbf5-D95A

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A1)	25S	polymer	3156	1020571.1	1		Saccharomyces cerevisiae (Baker's Yeast)
2	B (A3)	5S	polymer	121	38951.1	1		Saccharomyces cerevisiae (Baker's Yeast)
3	C (A4)	5.8S	polymer	158	50682.9	1		Saccharomyces cerevisiae (Baker's Yeast)
4	D (AA)	60S ribosomal protein L2-A	polymer	247	26643.7	1	UniProt (P0CX45) Pfam (PF00181) Pfam (PF03947)	Saccharomyces cerevisiae (Baker's yeast)	L5,Large ribosomal subunit protein uL2-A,RP8,YL6
5	E (AB)	60S ribosomal protein L3	polymer	386	43732.6	1	UniProt (P14126) Pfam (PF00297)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein uL3,Maintenance of killer protein 8,RP1,Trichodermin resistance protein,YL1
6	F (AC)	60S ribosomal protein L4-A	polymer	361	39027.9	1	UniProt (P10664) Pfam (PF00573) Pfam (PF14374)	Saccharomyces cerevisiae (Baker's yeast)	L2,Large ribosomal subunit protein uL4-A,RP2,YL2
7	G (AD)	60S ribosomal protein L5	polymer	292	33158.1	1	UniProt (P26321) Pfam (PF17144) Pfam (PF14204)	Saccharomyces cerevisiae (Baker's yeast)	L1,L1a,Large ribosomal subunit protein uL18,Ribosomal 5S RNA-binding protein,YL3
8	H (AE)	60S ribosomal protein L6-A	polymer	156	17579.7	1	UniProt (Q02326) Pfam (PF01159)	Saccharomyces cerevisiae (Baker's yeast)	L17,Large ribosomal subunit protein eL6-A,RP18,YL16
9	I (AF)	60S ribosomal protein L7-A	polymer	222	25240.4	1	UniProt (P05737) Pfam (PF08079) Pfam (PF00327)	Saccharomyces cerevisiae (Baker's yeast)	L6,Large ribosomal subunit protein uL30-A,RP11,YL8
10	J (AG)	60S ribosomal protein L8-A	polymer	230	25541.8	1	UniProt (P17076) Pfam (PF01248)	Saccharomyces cerevisiae (Baker's yeast)	L4,L4-2,L7a-1,Large ribosomal subunit protein eL8-A,Maintenance of killer protein 7,RP6,YL5
11	K (AH)	60S ribosomal protein L9-A	polymer	190	21491.9	1	UniProt (P05738) Pfam (PF00347)	Saccharomyces cerevisiae (Baker's yeast)	L8,Large ribosomal subunit protein uL6-A,RP24,YL11
12	L (AI)	60S ribosomal protein L10	polymer	205	23733.5	1	UniProt (P41805) Pfam (PF00252)	Saccharomyces cerevisiae (Baker's yeast)	L9,Large ribosomal subunit protein uL16,Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein
13	M (AJ)	60S ribosomal protein L11-A	polymer	169	19266.1	1	UniProt (P0C0W9) Pfam (PF00281) Pfam (PF00673)	Saccharomyces cerevisiae (Baker's yeast)	L16,Large ribosomal subunit protein uL5-A,RP39,YL22
14	N (AL)	60S ribosomal protein L13-A	polymer	193	21885.2	1	UniProt (Q12690) Pfam (PF01294)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL13-A
15	O (AM)	60S ribosomal protein L14-A	polymer	136	14976.8	1	UniProt (P36105) Pfam (PF00467) Pfam (PF01929)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL14-A
16	P (AN)	60S ribosomal protein L15-A	polymer	203	24351.2	1	UniProt (P05748) Pfam (PF00827)	Saccharomyces cerevisiae (Baker's yeast)	L13,Large ribosomal subunit protein eL15-A,RP15R,YL10,YP18
17	Q (AO)	60S ribosomal protein L16-A	polymer	197	22029.0	1	UniProt (P26784) Pfam (PF00572)	Saccharomyces cerevisiae (Baker's yeast)	L13a,L21,Large ribosomal subunit protein uL13-A,RP22,YL15
18	R (AP)	60S ribosomal protein L17-A	polymer	175	19687.4	1	UniProt (P05740) Pfam (PF00237)	Saccharomyces cerevisiae (Baker's yeast)	L20A,Large ribosomal subunit protein uL22-A,YL17
19	S (AQ)	60S ribosomal protein L18-A	polymer	185	20478.1	1	UniProt (P0CX49) Pfam (PF17135)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL18-A,RP28
20	T (AR)	60S ribosomal protein L19-A	polymer	188	21631.1	1	UniProt (P0CX82) Pfam (PF01280)	Saccharomyces cerevisiae (Baker's yeast)	L23,Large ribosomal subunit protein eL19-A,RP15L,RP33,YL14
21	U (AS)	60S ribosomal protein L20-A	polymer	172	20478.9	1	UniProt (P0CX23) Pfam (PF01775)	Saccharomyces cerevisiae (Baker's yeast)	L18a,Large ribosomal subunit protein eL20-A
22	V (AT)	60S ribosomal protein L21-A	polymer	159	18148.1	1	UniProt (Q02753) Pfam (PF01157)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL21-A
23	W (AU)	60S ribosomal protein L22-A	polymer	100	11263.9	1	UniProt (P05749) Pfam (PF01776)	Saccharomyces cerevisiae (Baker's yeast)	L1c,Large ribosomal subunit protein eL22-A,RP4,YL31
24	X (AV)	60S ribosomal protein L23-A	polymer	136	14362.8	1	UniProt (P0CX41) Pfam (PF00238)	Saccharomyces cerevisiae (Baker's yeast)	L17a,Large ribosomal subunit protein uL14-A,YL32
25	Y (AW)	60S ribosomal protein L24-A	polymer	63	7384.7	1	UniProt (P04449) Pfam (PF01246)	Saccharomyces cerevisiae (Baker's yeast)	L30,Large ribosomal subunit protein eL24-A,RP29,YL21
26	Z (AX)	60S ribosomal protein L25	polymer	121	13771.2	1	UniProt (P04456) Pfam (PF03939) Pfam (PF00276)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein uL23,RP16L,YL25,YP42'
27	AA (AY)	60S ribosomal protein L26-A	polymer	126	14134.6	1	UniProt (P05743) Pfam (PF00467) Pfam (PF16906)	Saccharomyces cerevisiae (Baker's yeast)	L33,Large ribosomal subunit protein uL24-A,YL33
28	BA (AZ)	60S ribosomal protein L27-A	polymer	135	15437.2	1	UniProt (P0C2H6) Pfam (PF01777)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL27-A
29	CA (Aa)	60S ribosomal protein L28	polymer	148	16630.5	1	UniProt (P02406) Pfam (PF00828)	Saccharomyces cerevisiae (Baker's yeast)	L27a,L29,Large ribosomal subunit protein uL15,RP44,RP62,YL24
30	DA (Ab)	60S ribosomal protein L29	polymer	58	6560.7	1	UniProt (P05747) Pfam (PF01779)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL29,YL43
31	EA (Ac)	60S ribosomal protein L30	polymer	97	10558.3	1	UniProt (P14120) Pfam (PF01248)	Saccharomyces cerevisiae (Baker's yeast)	L32,Large ribosomal subunit protein eL30,RP73,YL38
32	FA (Ad)	60S ribosomal protein L31-A	polymer	109	12649.8	1	UniProt (P0C2H8) Pfam (PF01198)	Saccharomyces cerevisiae (Baker's yeast)	L34,Large ribosomal subunit protein eL31-A,YL28
33	GA (Ae)	60S ribosomal protein L32	polymer	127	14478.1	1	UniProt (P38061) Pfam (PF01655)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL32
34	HA (Af)	60S ribosomal protein L33-A	polymer	106	12045.9	1	UniProt (P05744) Pfam (PF01247)	Saccharomyces cerevisiae (Baker's yeast)	L37,Large ribosomal subunit protein eL33-A,RP47,YL37
35	IA (Ag)	60S ribosomal protein L34-A	polymer	112	12608.8	1	UniProt (P87262) Pfam (PF01199)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL34-A
36	JA (Ah)	60S ribosomal protein L35-A	polymer	119	13811.4	1	UniProt (P0CX84) Pfam (PF00831)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein uL29-A
37	KA (Ai)	60S ribosomal protein L36-A	polymer	99	11020.1	1	UniProt (P05745) Pfam (PF01158)	Saccharomyces cerevisiae (Baker's yeast)	L39,Large ribosomal subunit protein eL36-A,YL39
38	LA (Aj)	60S ribosomal protein L37-A	polymer	87	9746.2	1	UniProt (P49166) Pfam (PF01907)	Saccharomyces cerevisiae (Baker's yeast)	L43,Large ribosomal subunit protein eL37-A,YL35,YP55
39	MA (Ak)	60S ribosomal protein L38	polymer	77	8714.4	1	UniProt (P49167) Pfam (PF01781)	Saccharomyces cerevisiae (Baker's yeast)	Large ribosomal subunit protein eL38
40	NA (Al)	60S ribosomal protein L39	polymer	50	6227.4	1	UniProt (P04650) Pfam (PF00832)	Saccharomyces cerevisiae (Baker's yeast)	L46,Large ribosomal subunit protein eL39,YL40
41	OA (Am)	60S ribosomal protein L40-A	polymer	52	6032.3	1	UniProt (P0CH08) Pfam (PF01020)	Saccharomyces cerevisiae (Baker's yeast)	CEP52,Large ribosomal subunit protein eL40-A
42	PA (An)	60S ribosomal protein L41-A	polymer	25	3354.2	1	UniProt (P0CX86) Pfam (PF05162)	Saccharomyces cerevisiae (Baker's yeast)	L47,Large ribosomal subunit protein eL41-A,YL41
43	QA (Ao)	60S ribosomal protein L42-A	polymer	105	12115.5	1	UniProt (P0CX27) Pfam (PF00935)	Saccharomyces cerevisiae (Baker's yeast)	L41,Large ribosomal subunit protein eL42-A,YL27,YP44
44	RA (Ap)	60S ribosomal protein L43-A	polymer	91	9981.8	1	UniProt (P0CX25) Pfam (PF01780)	Saccharomyces cerevisiae (Baker's yeast)	L37a,Large ribosomal subunit protein eL43-A,YL35
45	SA (BA)	40S ribosomal protein S0-A	polymer	206	22811.1	1	UniProt (P32905) Pfam (PF00318)	Saccharomyces cerevisiae (Baker's yeast)	Nucleic acid-binding protein NAB1A,Small ribosomal subunit protein uS2-A
46	TA (BB)	40S ribosomal protein S1-A	polymer	214	24312.2	1	UniProt (P33442) Pfam (PF01015)	Saccharomyces cerevisiae (Baker's yeast)	RP10A,Small ribosomal subunit protein eS1-A
47	UA (BC)	40S ribosomal protein S2	polymer	217	23213.0	1	UniProt (P25443) Pfam (PF00333) Pfam (PF03719)	Saccharomyces cerevisiae (Baker's yeast)	Omnipotent suppressor protein SUP44,RP12,S4,Small ribosomal subunit protein uS5,YS5
48	VA (BD)	40S ribosomal protein S3	polymer	223	24702.8	1	UniProt (P05750) Pfam (PF07650) Pfam (PF00189)	Saccharomyces cerevisiae (Baker's yeast)	RP13,Small ribosomal subunit protein uS3,YS3
49	WA (BE)	40S ribosomal protein S4-A	polymer	260	29338.1	1	UniProt (P0CX35) Pfam (PF08071) Pfam (PF01479) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121)	Saccharomyces cerevisiae (Baker's yeast)	RP5,S7,Small ribosomal subunit protein eS4-A,YS6
50	XA (BF)	40S ribosomal protein S5	polymer	206	22908.3	1	UniProt (P26783) Pfam (PF00177)	Saccharomyces cerevisiae (Baker's yeast)	RP14,S2,Small ribosomal subunit protein uS7,YS8
51	YA (BG)	40S ribosomal protein S6-A	polymer	226	25895.1	1	UniProt (P0CX37) Pfam (PF01092)	Saccharomyces cerevisiae (Baker's yeast)	RP9,S10,Small ribosomal subunit protein eS6-A,YS4
52	ZA (BH)	40S ribosomal protein S7-A	polymer	184	21000.5	1	UniProt (P26786) Pfam (PF01251)	Saccharomyces cerevisiae (Baker's yeast)	RP30,RP40,Small ribosomal subunit protein eS7-A
53	AB (BI)	40S ribosomal protein S8-A	polymer	188	21147.2	1	UniProt (P0CX39) Pfam (PF01201)	Saccharomyces cerevisiae (Baker's yeast)	RP19,S14,Small ribosomal subunit protein eS8-A,YS9
54	BB (BJ)	40S ribosomal protein S9-A	polymer	185	21210.7	1	UniProt (O13516) Pfam (PF00163) Pfam (PF01479)	Saccharomyces cerevisiae (Baker's yeast)	RP21,S13,Small ribosomal subunit protein uS4-A,YP28,YS11
55	CB (BK)	40S ribosomal protein S10-A	polymer	96	11571.1	1	UniProt (Q08745) Pfam (PF03501)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein eS10-A
56	DB (BL)	40S ribosomal protein S11-A	polymer	155	17654.7	1	UniProt (P0CX47) Pfam (PF16205) Pfam (PF00366)	Saccharomyces cerevisiae (Baker's yeast)	RP41,S18,Small ribosomal subunit protein uS17-A,YS12
57	EB (BM)	40S ribosomal protein S12	polymer	121	13028.0	1	UniProt (P48589) Pfam (PF01248)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein eS12
58	FB (BN)	40S ribosomal protein S13	polymer	150	16928.7	1	UniProt (P05756) Pfam (PF08069) Pfam (PF00312)	Saccharomyces cerevisiae (Baker's yeast)	S27a,Small ribosomal subunit protein uS15,YS15
59	GB (BO)	40S ribosomal protein S14-A	polymer	127	13446.4	1	UniProt (P06367) Pfam (PF00411)	Saccharomyces cerevisiae (Baker's yeast)	RP59A,Small ribosomal subunit protein uS11-A
60	HB (BP)	40S ribosomal protein S15	polymer	124	14155.7	1	UniProt (Q01855) Pfam (PF00203)	Saccharomyces cerevisiae (Baker's yeast)	RIG protein,RP52,S21,Small ribosomal subunit protein uS19,YS21
61	IB (BQ)	40S ribosomal protein S16-A	polymer	141	15659.2	1	UniProt (P0CX51) Pfam (PF00380)	Saccharomyces cerevisiae (Baker's yeast)	RP61R,Small ribosomal subunit protein uS9-A
62	JB (BR)	40S ribosomal protein S17-A	polymer	121	13911.2	1	UniProt (P02407) Pfam (PF00833)	Saccharomyces cerevisiae (Baker's yeast)	RP51A,Small ribosomal subunit protein eS17-A
63	KB (BS)	40S ribosomal protein S18-A	polymer	145	16940.4	1	UniProt (P0CX55) Pfam (PF00416)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein uS13-A
64	LB (BT)	40S ribosomal protein S19-A	polymer	141	15566.7	1	UniProt (P07280) Pfam (PF01090)	Saccharomyces cerevisiae (Baker's yeast)	RP55A,S16a,Small ribosomal subunit protein eS19-A,YP45,YS16A
65	MB (BU)	40S ribosomal protein S20	polymer	107	12190.2	1	UniProt (P38701) Pfam (PF00338)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein uS10
66	NB (BV)	40S ribosomal protein S21-A	polymer	87	9758.8	1	UniProt (P0C0V8) Pfam (PF01249)	Saccharomyces cerevisiae (Baker's yeast)	S26,Small ribosomal subunit protein eS21-A,YS25
67	OB (BW)	40S ribosomal protein S22-A	polymer	129	14518.9	1	UniProt (P0C0W1) Pfam (PF00410)	Saccharomyces cerevisiae (Baker's yeast)	RP50,S24,Small ribosomal subunit protein uS8-A,YP58,YS22
68	PB (BX)	40S ribosomal protein S23-A	polymer	144	15942.7	1	UniProt (P0CX29) Pfam (PF00164)	Saccharomyces cerevisiae (Baker's yeast)	RP37,S28,Small ribosomal subunit protein uS12-A,YS14
69	QB (BY)	40S ribosomal protein S24-A	polymer	134	15231.6	1	UniProt (P0CX31) Pfam (PF01282)	Saccharomyces cerevisiae (Baker's yeast)	RP50,Small ribosomal subunit protein eS24-A
70	RB (BZ)	40S ribosomal protein S25-A	polymer	69	7930.3	1	UniProt (Q3E792) Pfam (PF03297)	Saccharomyces cerevisiae (Baker's yeast)	RP45,S31,Small ribosomal subunit protein eS25-A,YS23
71	SB (Ba)	40S ribosomal protein S26-B	polymer	97	11023.0	1	UniProt (P39939) Pfam (PF01283)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein eS26-B
72	TB (Bb)	40S ribosomal protein S27-A	polymer	81	8762.2	1	UniProt (P35997) Pfam (PF01667)	Saccharomyces cerevisiae (Baker's yeast)	RP61,Small ribosomal subunit protein eS27-A,YS20
73	UB (Bc)	40S ribosomal protein S28-A	polymer	63	7116.3	1	UniProt (Q3E7X9) Pfam (PF01200)	Saccharomyces cerevisiae (Baker's yeast)	S33,Small ribosomal subunit protein eS28-A,YS27
74	VB (Bd)	40S ribosomal protein S29-A	polymer	53	6335.3	1	UniProt (P41057) Pfam (PF00253)	Saccharomyces cerevisiae (Baker's yeast)	S36,Small ribosomal subunit protein uS14-A,YS29
75	WB (Be)	40S ribosomal protein S30-A	polymer	60	6779.1	1	UniProt (P0CX33) Pfam (PF04758)	Saccharomyces cerevisiae (Baker's yeast)	Small ribosomal subunit protein eS30-A
76	XB (Bf)	40S ribosomal protein S31	polymer	57	6491.6	1	UniProt (P05759) Pfam (PF01599)	Saccharomyces cerevisiae (Baker's yeast)	CEP76,S37,Small ribosomal subunit protein eS31,YS24
77	YB (Bg)	Guanine nucleotide-binding protein subunit beta-like protein	polymer	312	34151.5	1	UniProt (P38011) Pfam (PF00400)	Saccharomyces cerevisiae (Baker's yeast)	Receptor for activated C kinase,Receptor of activated protein kinase C 1,RACK1,Small ribosomal subunit protein RACK1
78	ZB (Bh)	Suppressor protein STM1	polymer	89	9664.4	1	UniProt (P39015)	Saccharomyces cerevisiae (Baker's yeast)	3BP1,GU4 nucleic-binding protein 2,G4p2 protein,POP2 multicopy suppressor protein 4,Ribosomal subunits association factor,AF,TOM1 suppressor protein 1,Triplex-binding protein 1
79	AC (B5)	18S RIBOSOMAL RNA	polymer	1783	574905.3	1		Saccharomyces cerevisiae (Baker's yeast)	Baker's yeast
80	BC (A1)	4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione	non-polymer		281.3	1	Chemie (3HE)
81	AD, AE, AF, AG, AH... (A1, A4, Ba, B5, AB...)	MAGNESIUM ION	non-polymer		24.3	374	Chemie (MG)
82	BN, WM (Bb, Ao)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

AE: 2 - 176 (UniProt: Q02326)

PDB	External Database	Details
-	Lys 110	deletion
-	Leu 111	deletion
-	Thr 112	deletion
-	Lys 113	deletion
-	Lys 114	deletion
-	Glu 115	deletion
-	Lys 116	deletion
-	Lys 117	deletion
-	Glu 118	deletion
-	Ala 119	deletion
-	Asn 120	deletion
-	Leu 121	deletion
-	Phe 122	deletion
-	Pro 123	deletion
-	Glu 124	deletion
-	Gln 125	deletion
-	Gln 126	deletion
-	Asn 127	deletion
-	Lys 128	deletion

AI: 2 - 218 (UniProt: P41805)

PDB	External Database	Details
-	Met 102	deletion
-	Leu 103	deletion
-	Ser 104	deletion
-	Cys 105	deletion
-	Ala 106	deletion
-	Gly 107	deletion
-	Ala 108	deletion
-	Asp 109	deletion
-	Arg 110	deletion
-	Leu 111	deletion
-	Gln 112	deletion
-	Gln 113	deletion

AP: 2 - 184 (UniProt: P05740)

PDB	External Database	Details
-	Ala 156	deletion
-	Val 157	deletion
-	Ala 158	deletion
-	Lys 159	deletion
-	Ala 160	deletion
-	Ala 161	deletion
-	Glu 162	deletion
-	Lys 163	deletion

BI: 2 - 200 (UniProt: P0CX39)

PDB	External Database	Details
-	Lys 124	deletion
-	Lys 125	deletion
-	Asn 126	deletion
-	Val 127	deletion
-	Lys 128	deletion
-	Glu 129	deletion
-	Glu 130	deletion
-	Glu 131	deletion
-	Thr 132	deletion
-	Val 133	deletion
-	Ala 134	deletion

BR: 2 - 126 (UniProt: P02407)

PDB	External Database	Details
-	Ser 96	deletion
-	Asn 97	deletion
-	Gly 98	deletion
-	Val 99	deletion

Bf: 93 - 152 (UniProt: P05759)

PDB	External Database	Details
Ala 97	Lys 97	conflict
-	Cys 126	deletion
-	Gly 127	deletion
-	Ala 128	deletion

Contents of the asymmetric unit

Polymers	Number of chains	79
	Total formula weight	2938378.3
Non-Polymers*	Number of molecules	377
	Total formula weight	9502.2
All*	Total formula weight	2947880.6

*Water molecules are not included.