7N7U
Crystal Structure of SARS-CoV-2 NendoU in complex with LIZA-7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridylate-specific endoribonuclease | polymer | 349 | 39112.5 | 2 | UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus) | NendoU, Non-structural protein 15, nsp15 |
| 2 | C, D (A, B) | 1-[(2~{R},4~{S},5~{R})-5-[[(azanylidene-$l^{4}-azanylidene)amino]methyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione | non-polymer | 268.2 | 2 | Chemie (0MI) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 525 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 346 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78225.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 536.5 | |
| All* | Total formula weight | 78761.6 |
