7N7P

Cryo-EM structure of human TMEM120A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ion channel TACAN	polymer	356	42013.5	2	UniProt (Q9BXJ8) Pfam (PF07851) In PDB	Homo sapiens (Human)	Transmembrane protein 120A, TMEM120A, Transmembrane protein induced by tumor necrosis factor alpha
2	A, B	COENZYME A	non-polymer		767.5	2	Chemie (COA)

Sequence modifications

A, B: 2 - 343 (UniProt: Q9BXJ8)

PDB	External Database	Details
Met -12	-	initiating methionine
Asp -11	-	expression tag
Tyr -10	-	expression tag
Lys -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Lys -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ala 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84026.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1535.1
All*	Total formula weight	85562.0

*Water molecules are not included.