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7N7J

Crystal Structure of PI5P4KIIAlpha complex with AMPPNP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhosphatidylinositol 5-phosphate 4-kinase type-2 alphapolymer37743114.71UniProt (P48426)
Pfam (PF01504)
In PDB
Homo sapiens (Human)1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-Phosphate 4-Kinase,PI5P4Kalpha,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PI(5)P 4-kinase type II alpha,PIP4KII-alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha
2AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
3APHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4ASULFATE IONnon-polymer96.13Chemie (SO4)
5waterwater18.0182Chemie (HOH)
Sequence modifications
A: 33 - 405 (UniProt: P48426)
PDBExternal DatabaseDetails
Gly 29-expression tag
Ser 30-expression tag
His 31-expression tag
Met 32-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43114.7
Non-Polymers*Number of molecules6
Total formula weight904.3
All*Total formula weight44019.0
*Water molecules are not included.

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PDB entries from 2024-07-24

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