7N6F
Co-complex CYP46A1 with compound 3f
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cholesterol 24-hydroxylase | polymer | 474 | 54434.7 | 1 | UniProt (Q9Y6A2) Pfam (PF00067) In PDB | Homo sapiens (Human) | CH24H,Cholesterol 24-monooxygenase,Cholesterol 24S-hydroxylase,Cytochrome P450 46A1 |
2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
3 | A | (3-fluoroazetidin-1-yl){1-[4-(4-fluorophenyl)pyrimidin-5-yl]piperidin-4-yl}methanone | non-polymer | 358.4 | 1 | Chemie (0I1) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A: 28 - 494 (UniProt: Q9Y6A2)
PDB | External Database | Details |
---|---|---|
Met 21 | - | initiating methionine |
His 22 | - | expression tag |
His 23 | - | expression tag |
His 24 | - | expression tag |
His 25 | - | expression tag |
His 26 | - | expression tag |
His 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54434.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1591.5 | |
All* | Total formula weight | 56026.2 |