7N65
Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, E, I) | Envelope glycoprotein gp41 | polymer | 508 | 56846.6 | 3 | UniProt (A0A6H1VCM1) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, F, J (B, F, J) | Envelope glycoprotein gp41 | polymer | 161 | 18245.8 | 3 | UniProt (Q2N0S7) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | C, G, K (C, G, K) | Fab QA013.2 Heavy Chain, variable region | polymer | 128 | 14384.1 | 3 | Homo sapiens (Human) | ||
| 4 | D, H, L (D, H, L) | Fab QA013.2 Light Chain, , variable region | polymer | 108 | 11189.3 | 3 | Homo sapiens (Human) | ||
| 5 | BB, DA, FA, GA, GB... (1, d, f, g, 6...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 18 | In PDB GlyTouCan (G15407YE) | |||
| 6 | AA, BA, CA, EA, FB... (a, b, c, e, 5...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 21 | In PDB GlyTouCan (G42666HT) | |||
| 7 | AB, JA, S (0, j, S) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G07617FP) | |||
| 8 | CB, LA, U (2, l, U) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 9 | DB, MA, V (3, m, V) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G55220VL) | |||
| 10 | EB, NA, W (4, n, W) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 3 | In PDB GlyTouCan (G80966KZ) | |||
| 11 | LB, MB, NB, PB, QB... (A, B, E, F, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 12 | OB, SB, WB (C, G, K) | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) |
Sequence modifications
A, E, I: 31 - 505 (UniProt: A0A6H1VCM1)
B, F, J: 511 - 664 (UniProt: Q2N0S7)
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | initiating methionine |
| Asp -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Arg 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Cys 4 | - | expression tag |
| Cys 5 | - | expression tag |
| Val 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Cys 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Phe 14 | - | expression tag |
| Val 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Gln 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Ile 21 | - | expression tag |
| His 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Arg 24 | - | expression tag |
| Phe 25 | - | expression tag |
| Arg 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Arg 30 | - | expression tag |
| Ser 375 | Tyr 373 | conflict |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 504 | - | expression tag |
| Gly 505 | - | expression tag |
| Arg 506 | - | expression tag |
| Arg 507 | - | expression tag |
| Arg 508 | - | expression tag |
| Arg 509 | - | expression tag |
| Arg 510 | - | expression tag |
| Pro 559 | Ile 556 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 301997.4 | |
| Branched | Number of molecules | 51 |
| Total formula weight | 33805.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2531.3 | |
| All* | Total formula weight | 338333.7 |
