7N4N
BACE-2 in complex with ligand 36
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-secretase 2 | polymer | 386 | 42105.4 | 1 | UniProt (Q9Y5Z0) Pfam (PF00026) | Homo sapiens (Human) | Aspartic-like protease 56 kDa,Aspartyl protease 1,ASP1,Asp 1,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,DRAP,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase |
| 2 | B (D) | Xaperone | polymer | 114 | 12106.4 | 1 | Homo sapiens (human) | ||
| 3 | C (A) | N-{3-[(2S,5R)-6-amino-2-(fluoromethyl)-5-(methanesulfonyl)-5-methyl-2,3,4,5-tetrahydropyridin-2-yl]-4-fluorophenyl}-6-methoxypyrimidine-4-carboxamide | non-polymer | 467.5 | 1 | Chemie (0BK) | |||
| 4 | D, E, F, G (A, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | H, I (A, D) | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54211.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 715.8 | |
| All* | Total formula weight | 54927.6 |
