7N4I
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | WRAIR-2057 Antibody Fab Heavy Chain | polymer | 226 | 24108.0 | 1 | Homo sapiens (human) | ||
| 2 | B (L) | WRAIR-2057 Antibody Fab Light Chain | polymer | 214 | 23272.7 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Spike protein S1 | polymer | 205 | 23073.8 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 4 | D (A) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F (H, L) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | G, H, I (H, L, C) | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
C: 331 - 527 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 528 | - | expression tag |
| Ser 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 70454.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 71225.3 |
