7N4I

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	WRAIR-2057 Antibody Fab Heavy Chain	polymer	226	24108.0	1		Homo sapiens (human)
2	L	WRAIR-2057 Antibody Fab Light Chain	polymer	214	23272.7	1		Homo sapiens (human)
3	C	Spike protein S1	polymer	205	23073.8	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
4	A	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	H, L	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6		water	water		18.0	251	Chemie (HOH)

Sequence modifications

C: 331 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 528	-	expression tag
Ser 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70454.5
Branched	Number of molecules	1
	Total formula weight	586.5
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	71225.3

*Water molecules are not included.