7N3U
Crystal structure of human WEE1 kinase domain in complex with ZN-c3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Wee1-like protein kinase | polymer | 285 | 32168.6 | 1 | UniProt (P30291) Pfam (PF00069) | Homo sapiens (Human) | WEE1hu,Wee1A kinase |
| 2 | B (A) | 1-[(7R)-7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one | non-polymer | 526.6 | 1 | Chemie (05J) | |||
| 3 | C (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32168.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 526.6 | |
| All* | Total formula weight | 32695.3 |
