7N3I
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment C098
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Spike protein S1 | polymer | 212 | 24004.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus) | |
| 2 | B (H) | C098 Fab heavy chain | polymer | 230 | 24452.3 | 1 | Homo sapiens | ||
| 3 | C (L) | C098 Fab light chain | polymer | 215 | 23317.8 | 1 | Homo sapiens | ||
| 4 | D (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (C, H, L) | water | water | 18.0 | 480 | Chemie (HOH) |
Sequence modifications
C: 328 - 533 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71775.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 71996.2 |
