7N2C
Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2)
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 16 | 16S rRNA | polymer | 1534 | 497390.9 | 1 | GenBank (1789840096) | Escherichia coli K-12 | |
2 | SB | 30S ribosomal protein S2 | polymer | 241 | 26781.7 | 1 | UniProt (P0A7V0) Pfam (PF00318) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS2 |
3 | SC | 30S ribosomal protein S3 | polymer | 233 | 26031.3 | 1 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS3 |
4 | SD | 30S ribosomal protein S4 | polymer | 206 | 23514.2 | 1 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS4 |
5 | SE | 30S ribosomal protein S5 | polymer | 167 | 17629.4 | 1 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS5 |
6 | SF | 30S ribosomal protein S6 | polymer | 135 | 15727.5 | 1 | UniProt (P02358) Pfam (PF01250) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein bS6 |
7 | SG | 30S ribosomal protein S7 | polymer | 179 | 20055.2 | 1 | UniProt (P02359) Pfam (PF00177) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS7 |
8 | SH | 30S ribosomal protein S8 | polymer | 130 | 14146.6 | 1 | UniProt (P0A7W7) Pfam (PF00410) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS8 |
9 | SI | 30S ribosomal protein S9 | polymer | 130 | 14886.3 | 1 | UniProt (P0A7X3) Pfam (PF00380) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS9 |
10 | SJ | 30S ribosomal protein S10 | polymer | 103 | 11755.6 | 1 | UniProt (P0A7R5) Pfam (PF00338) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS10 |
11 | SK | 30S ribosomal protein S11 | polymer | 129 | 13871.0 | 1 | UniProt (P0A7R9) Pfam (PF00411) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS11 |
12 | SL | 30S ribosomal protein S12 | polymer | 124 | 13814.2 | 1 | UniProt (A0A4S5B3M5) In PDB | Escherichia coli (strain K12) | |
13 | SM | 30S ribosomal protein S13 | polymer | 118 | 13128.5 | 1 | UniProt (P0A7S9) Pfam (PF00416) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS13 |
14 | SN | 30S ribosomal protein S14 | polymer | 101 | 11606.6 | 1 | UniProt (P0AG59) Pfam (PF00253) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS14 |
15 | SO | 30S ribosomal protein S15 | polymer | 89 | 10290.8 | 1 | UniProt (P0ADZ4) Pfam (PF00312) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS15 |
16 | SP | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (P0A7T3) Pfam (PF00886) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein bS16 |
17 | SQ | 30S ribosomal protein S17 | polymer | 84 | 9724.5 | 1 | UniProt (P0AG63) Pfam (PF00366) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein uS17 |
18 | SR | 30S ribosomal protein S18 | polymer | 75 | 9005.5 | 1 | UniProt (P0A7T7) Pfam (PF01084) In PDB | Escherichia coli (strain K12) | |
19 | SS | 30S ribosomal protein S19 | polymer | 92 | 10455.4 | 1 | UniProt (P0A7U3) Pfam (PF00203) In PDB | Escherichia coli (strain K12) | |
20 | ST | 30S ribosomal protein S20 | polymer | 87 | 9708.5 | 1 | UniProt (P0A7U7) Pfam (PF01649) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein bS20 |
21 | SU | 30S ribosomal protein S21 | polymer | 71 | 8524.0 | 1 | UniProt (P68679) Pfam (PF01165) In PDB | Escherichia coli (strain K12) | Small ribosomal subunit protein bS21 |
22 | mR | Chains: mR | polymer | 60 | 19128.4 | 1 | Escherichia coli K-12 | ||
23 | 23 | 23S rRNA | polymer | 2904 | 941811.6 | 1 | GenBank (802133627) | Escherichia coli K-12 | |
24 | 5 | 5S rRNA | polymer | 120 | 38790.1 | 1 | GenBank (991970073) | Escherichia coli K-12 | |
25 | LA | 50S ribosomal protein L1 | polymer | 234 | 24765.7 | 1 | UniProt (A0A4S5ALA4) In PDB | Escherichia coli (strain K12) | |
26 | LB | 50S ribosomal protein L2 | polymer | 273 | 29923.6 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) In PDB | Escherichia coli (strain K12) | |
27 | LC | 50S ribosomal protein L3 | polymer | 209 | 22277.5 | 1 | UniProt (P60438) Pfam (PF00297) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL3 |
28 | LD | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (P60723) Pfam (PF00573) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL4 |
29 | LE | 50S ribosomal protein L5 | polymer | 179 | 20333.6 | 1 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) In PDB | Escherichia coli (strain K12) | |
30 | LF | 50S ribosomal protein L6 | polymer | 177 | 18932.8 | 1 | UniProt (P0AG55) Pfam (PF00347) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL6 |
31 | LG | 50S ribosomal protein L7/L12 | polymer | 121 | 12309.2 | 1 | UniProt (P0A7K2) Pfam (PF16320) Pfam (PF00542) In PDB | Escherichia coli (strain K12) | L8 |
32 | LI | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL9 |
33 | LJ | 50S ribosomal protein L10 | polymer | 165 | 17736.6 | 1 | UniProt (P0A7J3) Pfam (PF00466) In PDB | Escherichia coli (strain K12) | 50S ribosomal protein L8,Large ribosomal subunit protein uL10 |
34 | LK | 50S ribosomal protein L11 | polymer | 142 | 14894.4 | 1 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL11 |
35 | LM | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (P0AA10) Pfam (PF00572) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL13 |
36 | LN | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (P0ADY3) Pfam (PF00238) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL14 |
37 | LO | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL15 |
38 | LP | 50S ribosomal protein L16 | polymer | 136 | 15327.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) In PDB | Escherichia coli (strain K12) | |
39 | LQ | 50S ribosomal protein L17 | polymer | 127 | 14393.7 | 1 | UniProt (P0AG44) Pfam (PF01196) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL17 |
40 | LR | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (P0C018) Pfam (PF00861) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL18 |
41 | LS | 50S ribosomal protein L19 | polymer | 115 | 13159.3 | 1 | UniProt (P0A7K6) Pfam (PF01245) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL19 |
42 | LT | 50S ribosomal protein L20 | polymer | 118 | 13528.0 | 1 | UniProt (P0A7L3) Pfam (PF00453) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL20 |
43 | LU | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (P0AG48) Pfam (PF00829) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL21 |
44 | LV | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL22 |
45 | LW | 50S ribosomal protein L23 | polymer | 100 | 11222.2 | 1 | UniProt (P0ADZ0) Pfam (PF00276) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL23 |
46 | LX | 50S ribosomal protein L24 | polymer | 104 | 11339.3 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL24 |
47 | LY | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL25 |
48 | La | 50S ribosomal protein L27 | polymer | 85 | 9146.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL27 |
49 | Lb | 50S ribosomal protein L28 | polymer | 78 | 9027.6 | 1 | UniProt (P0A7M2) Pfam (PF00830) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL28 |
50 | Lc | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (P0A7M6) Pfam (PF00831) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL29 |
51 | Ld | 50S ribosomal protein L30 | polymer | 59 | 6554.8 | 1 | UniProt (P0AG51) Pfam (PF00327) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein uL30 |
52 | Le | 50S ribosomal protein L31 | polymer | 70 | 7887.1 | 1 | UniProt (P0A7M9) Pfam (PF01197) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL31-A |
53 | Lf | 50S ribosomal protein L32 | polymer | 57 | 6463.4 | 1 | UniProt (P0A7N4) Pfam (PF01783) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL32 |
54 | Lg | 50S ribosomal protein L33 | polymer | 55 | 6388.6 | 1 | UniProt (P0A7N9) Pfam (PF00471) In PDB | Escherichia coli K-12 | |
55 | Lh | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (P0A7P5) Pfam (PF00468) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL34 |
56 | Li | 50S ribosomal protein L35 | polymer | 65 | 7313.0 | 1 | UniProt (P0A7Q1) Pfam (PF01632) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL35,Ribosomal protein A |
57 | Lj | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) In PDB | Escherichia coli (strain K12) | Large ribosomal subunit protein bL36-A,Ribosomal protein B |
58 | EF | Elongation factor G | polymer | 704 | 77632.1 | 1 | UniProt (P0A6M8) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) In PDB | Escherichia coli (strain K12) | EF-G |
59 | Pp | Polypeptide | polymer | 3 | 425.6 | 1 | Escherichia coli K-12 | ||
60 | Pt | Chains: Pt | polymer | 76 | 24703.8 | 1 | Escherichia coli | ||
61 | Dt | tRNA | polymer | 76 | 24771.0 | 1 | Escherichia coli | ||
62 | 23, 16, LC | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 21 | Chemie (PUT) | |||
63 | 16, SN, 23, EF, 5... | MAGNESIUM ION | non-polymer | 24.3 | 197 | Chemie (MG) | |||
64 | Le, SB, Lj | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
65 | 23 | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
66 | 23 | SPERMIDINE | non-polymer | 145.2 | 3 | Chemie (SPD) | |||
67 | EF | FUSIDIC ACID | non-polymer | 516.7 | 1 | Chemie (FUA) | |||
68 | EF | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) |
Sequence modifications
EF: 1 - 704 (UniProt: P0A6M8)
PDB | External Database | Details |
---|---|---|
Ser 1 | Met 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 61 |
Total formula weight | 2354385.6 | |
Non-Polymers* | Number of molecules | 228 |
Total formula weight | 9245.5 | |
All* | Total formula weight | 2363631.1 |