7N2B

A DARPin semi-rigidly fused to the 3TEL crystallization chaperone

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transcription factor ETV6,Transcription factor ETV6,Transcription factor ETV6,3TEL-rigid-DARPin	polymer	416	46817.6	2	UniProt (P41212) Pfam (PF02198) In PDB	Homo sapiens (Human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,ETS translocation variant 6,ETS-related protein Tel1,Tel,ETS translocation variant 6,ETS-related protein Tel1,Tel

Sequence modifications

A, B: 1 - 75 (UniProt: P41212)

PDB	External Database	Details
Gly 0	-	expression tag
Glu 66	Val 112	engineered mutation

A, B: 86 - 163 (UniProt: P41212)

PDB	External Database	Details
Lys 76	-	linker
Gln 77	-	linker
Arg 78	-	linker
Pro 79	-	linker
Gly 80	-	linker
Gly 81	-	linker
Gly 82	-	linker
Gly 83	-	linker
Ser 84	-	linker
Thr 85	-	linker

A, B: 171 - 248 (UniProt: P41212)

PDB	External Database	Details
Pro 164	-	linker
Gly 165	-	linker
Gly 166	-	linker
Gly 167	-	linker
Gly 168	-	linker
Ser 169	-	linker
Thr 170	-	linker

A, B: 249 - 415 (PDB: 7N2B)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93635.1
All*	Total formula weight	93635.1

*Water molecules are not included.