7N1Y
Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1305 | 144368.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
2 | D, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 16 | In PDB GlyTouCan (G42666HT) | |||
3 | I, R, Z | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
4 | a, b, J, K, S... | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G62182OO) | |||
5 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 32 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1273 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
- | His 69 | deletion |
- | Val 70 | deletion |
- | Tyr 144 | deletion |
Tyr 501 | Asn 501 | conflict |
Asp 570 | Ala 570 | conflict |
Gly 614 | Asp 614 | conflict |
His 681 | Pro 681 | conflict |
Ile 716 | Thr 716 | conflict |
Ala 982 | Ser 982 | conflict |
His 1118 | Asp 1118 | conflict |
Ser 1274 | - | expression tag |
Gly 1275 | - | expression tag |
Gly 1276 | - | expression tag |
Gly 1277 | - | expression tag |
Ser 1278 | - | expression tag |
Ala 1279 | - | expression tag |
Trp 1280 | - | expression tag |
Ser 1281 | - | expression tag |
His 1282 | - | expression tag |
Pro 1283 | - | expression tag |
Gln 1284 | - | expression tag |
Phe 1285 | - | expression tag |
Glu 1286 | - | expression tag |
Lys 1287 | - | expression tag |
Gly 1288 | - | expression tag |
Gly 1289 | - | expression tag |
Gly 1290 | - | expression tag |
Ser 1291 | - | expression tag |
Gly 1292 | - | expression tag |
Gly 1293 | - | expression tag |
Gly 1294 | - | expression tag |
Ser 1295 | - | expression tag |
Gly 1296 | - | expression tag |
Gly 1297 | - | expression tag |
Ser 1298 | - | expression tag |
Ser 1299 | - | expression tag |
Ala 1300 | - | expression tag |
Trp 1301 | - | expression tag |
Ser 1302 | - | expression tag |
His 1303 | - | expression tag |
Pro 1304 | - | expression tag |
Gln 1305 | - | expression tag |
Phe 1306 | - | expression tag |
Glu 1307 | - | expression tag |
Lys 1308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 433105.5 | |
Branched | Number of molecules | 25 |
Total formula weight | 12021.3 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 7078.7 | |
All* | Total formula weight | 452205.5 |