7N1R
A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Endoplasmic reticulum chaperone BiP | polymer | 606 | 67238.0 | 2 | UniProt (P11021) Pfam (PF00012) In PDB | Homo sapiens (Human) | 78 kDa glucose-regulated protein,GRP-78,Binding-immunoglobulin protein,BiP,Heat shock protein 70 family protein 5,HSP70 family protein 5,Heat shock protein family A member 5,Immunoglobulin heavy chain-binding protein |
| 2 | A, B | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 3 | B, A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | B, A | PHOSPHATE ION | non-polymer | 95.0 | 14 | Chemie (PO4) | |||
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | B, A | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 7 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | water | water | 18.0 | 1068 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 629 (UniProt: P11021)
| PDB | External Database | Details |
|---|---|---|
| Ser 24 | - | expression tag |
| Val 453 | Thr 453 | conflict |
| Gly 454 | Ala 454 | conflict |
| Gly 455 | Ser 455 | conflict |
| - | Asp 456 | deletion |
| - | Asn 457 | deletion |
| - | Gln 458 | deletion |
| - | Pro 459 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 134476.0 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 3491.9 | |
| All* | Total formula weight | 137967.9 |
