7N0Z

Structure of PPM1H phosphatase with manganese ions at the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein phosphatase 1H	polymer	451	50362.0	2	UniProt (Q9ULR3) Pfam (PF00481) In PDB	Homo sapiens (Human)
2	A, B	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4		water	water		18.0	211	Chemie (HOH)

Sequence modifications

A, B: 33 - 222 (UniProt: Q9ULR3)

PDB	External Database	Details
Gly 29	-	expression tag
Ser 30	-	expression tag
His 31	-	expression tag
Met 32	-	expression tag
Ala 56	Cys 56	engineered mutation

A, B: 227 - 514 (UniProt: Q9ULR3)

PDB	External Database	Details
Gly 223	-	linker
Ser 224	-	linker
Gly 225	-	linker
Ser 226	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100724.0
Non-Polymers*	Number of molecules	8
	Total formula weight	378.2
All*	Total formula weight	101102.2

*Water molecules are not included.