7N0V

Complex of recombinant Bet v 1 with Fab fragment of REGN5715

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	REGN5715 Fab heavy chain	polymer	225	24322.2	1		Mus musculus
2	L	REGN5715 Fab light chain	polymer	215	23447.0	1		Mus musculus
3	C	Major pollen allergen Bet v 1-A	polymer	187	20743.1	1	UniProt (P15494) Pfam (PF00407) In PDB	Betula pendula (European white birch Betula verrucosa)	Allergen Bet v I-A

Sequence modifications

C: 1 - 159 (UniProt: P15494)

PDB	External Database	Details
Leu 62	Phe 63	engineered mutation
Glu 160	-	expression tag
Gln 161	-	expression tag
Lys 162	-	expression tag
Leu 163	-	expression tag
Ile 164	-	expression tag
Ser 165	-	expression tag
Glu 166	-	expression tag
Glu 167	-	expression tag
Asp 168	-	expression tag
Leu 169	-	expression tag
Gly 170	-	expression tag
Gly 171	-	expression tag
Glu 172	-	expression tag
Gln 173	-	expression tag
Lys 174	-	expression tag
Leu 175	-	expression tag
Ile 176	-	expression tag
Ser 177	-	expression tag
Glu 178	-	expression tag
Glu 179	-	expression tag
Asp 180	-	expression tag
Leu 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	68512.3
All*	Total formula weight	68512.3

*Water molecules are not included.