7N0B

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (WT)-RNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Non-structural protein 10	polymer	139	14802.9	1	UniProt (P0DTD1) Pfam (PF09401)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	nsp10,Growth factor-like peptide,GFL
2	B (B)	Proofreading exoribonuclease	polymer	527	59887.5	1	UniProt (P0DTD1) Pfam (PF06471)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	ExoN,Guanine-N7 methyltransferase,Non-structural protein 14,nsp14
3	C (T)	RNA (5'-R(*AP*UP*GP*UP*GP*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*U)-3')	polymer	38	12246.2	1		Severe acute respiratory syndrome coronavirus 2
4	D (D)	RNA (5'-R(*AP*GP*AP*AP*GP*CP*UP*AP*UP*UP*AP*AP*AP*AP*UP*CP*AP*CP*C)-3')	polymer	33	10459.3	1		Severe acute respiratory syndrome coronavirus 2
5	E, F, I, J, K (A, B)	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
6	G, H (B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
7	L (D)	water	water		18.0	1	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97395.9
Non-Polymers*	Number of molecules	7
	Total formula weight	407.2
All*	Total formula weight	97803.1

*Water molecules are not included.